Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)
Public ClinicalTrials.gov record NCT07284602. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Head-to-Head Phase 3 Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone at 52 Weeks in Adults With Idiopathic Pulmonary Fibrosis (SURPASS-IPF)
Study identification
- NCT ID
- NCT07284602
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- PureTech
- Industry
- Enrollment
- 1,100 participants
Conditions and interventions
Conditions
Interventions
- Deupirfenidone Drug
- Pirfenidone (PFD) Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 25, 2026
- Primary completion
- May 31, 2029
- Completion
- Jun 30, 2029
- Last update posted
- Jul 16, 2026
2026 – 2029
United States locations
- U.S. sites
- 9
- U.S. states
- 6
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Palmtree Clinical Research Inc. | Palm Spring | California | 92262 | Recruiting |
| Paradigm Clinical Research Centers LLC | Redding | California | 96001 | Recruiting |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | Recruiting |
| Clinical Research Associates of Central PA | DuBois | Pennsylvania | 15801 | Recruiting |
| Clinical Research of Rock Hill | Rock Hill | South Carolina | 29732 | Recruiting |
| Clinical Trials Center of Middle Tennesee LLC | Franklin | Tennessee | 37067 | Recruiting |
| Premier Pulmonary Critical Care and Sleep Medicine | Denison | Texas | 75020 | Recruiting |
| Renovatio Clinical | The Woodlands | Texas | 77380 | Recruiting |
| Renovatio Clinical | Webster | Texas | 77598 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07284602, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 16, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07284602 live on ClinicalTrials.gov.