ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
Public ClinicalTrials.gov record NCT07284667. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled, Parallel Group, Efficacy and Safety Study of ACP-211 Monotherapy in Adults With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to learn if ACP-211 can help treat adults with major depressive disorder (MDD) who have not improved with antidepressant therapy (ADT), including those with treatment resistant depression (TRD). The main questions the study aims to answer are: * Does ACP-211 work better than a placebo (a look-alike capsule with no medicine) to reduce symptoms of depression? * What adverse events do participants have when taking ACP-211?
Study identification
- NCT ID
- NCT07284667
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 153 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 14, 2025 (Actual)
- Primary completion
- Aug 2027 (Estimated)
- Completion
- Sep 2027 (Estimated)
- Last update posted
- Oct 5, 2026
2025 – 2027
United States locations
- U.S. sites
- 28
- U.S. states
- 15
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | Withdrawn |
| Inland Psychiatric Medical Group | Chino | California | 91710 | Recruiting |
| Behavioral Research Specialists, LLC | Glendale | California | 91107 | Recruiting |
| Kadima Neuropsychiatry Institute | La Jolla | California | 92037 | Recruiting |
| PNS Clinical Research LLC dba ATP Clinical Research | Orange | California | 92866 | Recruiting |
| Focus Clinical Research, LLC d/b/a Alliance Clinical West Hills | West Hills | California | 91307 | Recruiting |
| Mountain View Clinical Research | Denver | Colorado | 80209 | Recruiting |
| New Access Research and Medical Services, Inc. | Fort Myers | Florida | 33901 | Recruiting |
| The Medici Medical Research | Hollywood | Florida | 33021 | Recruiting |
| Sandhill Research, LLC/DBA Accel Research Sites | Largo | Florida | 33777 | Withdrawn |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | Recruiting |
| IPTB Clinical Research | Tampa | Florida | 33629 | Recruiting |
| Neuroscience Research Institute, Inc. | West Palm Beach | Florida | 33407 | Recruiting |
| Adams Clinical, Inc. | Watertown | Massachusetts | 02472 | Recruiting |
| Vitalix Clinical, Inc. | Worcester | Massachusetts | 01608 | Recruiting |
| Precise Research Centers | Flowood | Mississippi | 39232 | Recruiting |
| St. Charles Psychiatric Associates, Inc. dba Midwest Research Group | Saint Charles | Missouri | 63304 | Recruiting |
| Alivation Research, LLC | Lincoln | Nebraska | 68526 | Recruiting |
| Redbird Research LLC | Las Vegas | Nevada | 89134 | Recruiting |
| CenExel Hassman Research Institute, LLC | Marlton | New Jersey | 08053 | Withdrawn |
| Integrative Clinical Trials LLC | Brooklyn | New York | 11229 | Recruiting |
| Magnolia Clinical Research, LLC | Cary | North Carolina | 27511 | Recruiting |
| Neuro-Behavioral Clinical Research | North Canton | Ohio | 44720 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Dynamed Clinical Research LP d/b/a DM Clinical Research | Houston | Texas | 77081 | Withdrawn |
| Olympus Clinical Research, LLC | Katy | Texas | 77450 | Recruiting |
| Family Psychiatry of The Woodlands | The Woodlands | Texas | 77381 | Recruiting |
| Aura Wellness | Salt Lake City | Utah | 84105 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07284667, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 5, 2026 · Synced Oct 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07284667 live on ClinicalTrials.gov.