Phase 3 Trial of VMX-C001 vs Usual Pharmacological Care in Patients Taking a FXa Direct Oral Anticoagulant Who Require Urgent Surgery With or Without Heparin.
Public ClinicalTrials.gov record NCT07288489. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Prospective Randomised Clinical Trial of VMX-C001 vs Usual Pharmacological Care in Patients Receiving a FXa Direct Oral Anticoagulant (FXa DOAC) Who Require Urgent Surgery or Other Invasive Procedure That is Associated With a High Risk of Bleeding, With or Without Planned Administration of Heparin (EQUILIBRIX-S)
Study identification
- NCT ID
- NCT07288489
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- VarmX B.V.
- Industry
- Enrollment
- 800 participants
Conditions and interventions
Conditions
Interventions
- Usual Pharmacological Care Drug
- VMX-C001 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2026
- Primary completion
- Dec 31, 2028
- Completion
- Dec 31, 2030
- Last update posted
- Feb 26, 2026
2026 – 2031
United States locations
- U.S. sites
- 16
- U.S. states
- 11
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Chandler Regional Medical Center (CRMC) | Chandler | Arizona | 85224 | — |
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| HonorHealth John C Lincoln Medical Center | Phoenix | Arizona | 85020 | — |
| Stanford Hospital and Clinics | Stanford | California | 94305 | — |
| Denver Metro Orthopedics, P.C. - Englewood Location | Englewood | Colorado | 80113 | — |
| Medical Center of the Rockies | Fort Collins | Colorado | 80523 | — |
| Christiana Care | Newark | Delaware | 19718 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| University of Iowa Health Care | Iowa City | Iowa | 52242 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beaumont Hospital, Royal Oak | Royal Oak | Michigan | 48073 | — |
| William Beaumont Hospital - Troy Campus | Troy | Michigan | 48085 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| The University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73126 | — |
| Texas Tech University Health Sciences Center - El Paso | El Paso | Texas | 79905 | — |
| The University of Texas McGovern Medical School at Houston | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07288489, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 26, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07288489 live on ClinicalTrials.gov.