ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Public ClinicalTrials.gov record NCT07294170. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol for an Exploratory, Phase 2a, Proof-of-Concept Platform Study to Evaluate the Safety, Tolerability, and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life.
Study identification
- NCT ID
- NCT07294170
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 70 participants
Conditions and interventions
Conditions
Interventions
- Efgartigimod IV Biological
- Empasiprubart IV Biological
- Placebo IV Other
- Efgartigimod PH20 SC PFS Biological
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 19, 2025 (Actual)
- Primary completion
- Mar 7, 2028 (Estimated)
- Completion
- Mar 7, 2028 (Estimated)
- Last update posted
- Oct 16, 2026
2025 – 2028
United States locations
- U.S. sites
- 15
- U.S. states
- 10
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Profound Research LLC - Carlsbad | Carlsbad | California | 92011 | Recruiting |
| Visionary Investigators Network | Miami | Florida | 33133 | Recruiting |
| Visionary Investigators Network | Miami | Florida | 33180 | Recruiting |
| University of South Florida | Tampa | Florida | 33620 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114-2621 | Recruiting |
| Henry Ford Health System | Detroit | Michigan | 48202-2608 | Recruiting |
| Profound Research LLC at Las Vegas Neurology Center | Las Vegas | Nevada | 89106 | Recruiting |
| Dent Neurologic Institute - Amherst | Amherst | New York | 14226 | Recruiting |
| University of North Carolina at Chapel Hill-170 Manning Dr. | Chapel Hill | North Carolina | 27514-4221 | Recruiting |
| Duke Early Phase Clinical Research Unit - PPDS | Durham | North Carolina | 27710-0001 | Recruiting |
| University of Cincinnati Medical Center - Goodman St | Cincinnati | Ohio | 45219=2364 | Recruiting |
| Ohio State Martha Morehouse Outpatient Care | Columbus | Ohio | 43221-3502 | Recruiting |
| Erlanger Health System | Chattanooga | Tennessee | 37403-2136 | Recruiting |
| National Neuromuscular Research Institute | Austin | Texas | 78759 | Recruiting |
| University of Texas- San Antonio - Health Science Center - PPDS | San Antonio | Texas | 78229 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07294170, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07294170 live on ClinicalTrials.gov.