ClinicalTrials.gov record
A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age
ClinicalTrials.gov ID: NCT07300839
Public ClinicalTrials.gov record NCT07300839. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:29 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL STUDY EVALUATING THE SAFETY, TOLERABILITY, IMMUNOGENICITY AND EFFICACY OF A VARIANT-ADAPTED BNT162B2 VACCINE IN HEALTHY PARTICIPANTS 50 THROUGH 64 YEARS OF AGE
Study identification
- NCT ID
- NCT07300839
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- BioNTech SE
- Industry
- Enrollment
- 5,240 participants
Conditions and interventions
Conditions
Interventions
- BNT162b2 Vaccine Biological
- Placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 9, 2025
- Primary completion
- Jul 30, 2026
- Completion
- Jul 30, 2026
- Last update posted
- Apr 12, 2026
2025 – 2026
United States locations
- U.S. sites
- 196
- U.S. states
- 39
- U.S. cities
- 151
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| North Alabama Research Center | Athens | Alabama | 35611 | — |
| Simon Williamson Clinic / Synexus Clinical Research US, Inc. | Birmingham | Alabama | 35211 | — |
| Accel Research Sites - Birmingham Clinical Research Unit | Birmingham | Alabama | 35216 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| AMR Clinical | Daphne | Alabama | 36526 | — |
| Medical Affiliated Research Center | Huntsville | Alabama | 35801 | — |
| AMR Clinical | Mobile | Alabama | 36608 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | — |
| Epic Medical Research-Sun City | Sun City | Arizona | 85351 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Synexus Clinical Research US, Inc./Orange Grove Family Practice | Tucson | Arizona | 85741 | — |
| Woodland International Research Group, LLC | Little Rock | Arkansas | 72211 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Velocity Clinical Research, Chula Vista | Chula Vista | California | 91911 | — |
| West Coast Research | Dublin | California | 94568 | — |
| Triallogix Medical Corporation | Fullerton | California | 92835 | — |
| Upper Echelon Medical | Fullerton | California | 92835 | — |
| Marvel Clinical Research | Huntington Beach | California | 92647 | — |
| Eximia Research-CA, LLC | La Mesa | California | 91942 | — |
| Velocity Clinical Research, Los Angeles | Los Angeles | California | 90057 | — |
| Leading Edge Research | Los Angeles | California | 91316 | — |
| ImmuniMet | Modesto | California | 95350 | — |
| Carbon Health - North Hollywood - NoHo West | North Hollywood | California | 91606 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | — |
| Northern California Research - Sacramento | Sacramento | California | 95821 | — |
| Velocity Clinical Research, San Bernardino | San Bernardino | California | 92408 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92123 | — |
| Med Partners, Inc. dba Premiere Medical Center of Burbank, Inc. | Toluca Lake | California | 91602 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Legacy Clinical Trials | Colorado Springs | Colorado | 80909 | — |
| Tekton Research, LLC. | Fort Collins | Colorado | 80525 | — |
| Tekton Research, LLC. | Longmont | Colorado | 80501 | — |
| Paradigm Clinical Research Centers, LLC | Wheat Ridge | Colorado | 80033 | — |
| Clinical Research Consulting | Milford | Connecticut | 06460 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Washington Health Institute | Washington D.C. | District of Columbia | 20017 | — |
| International Clinical Research - FL, LLC | Altamonte Springs | Florida | 32701 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| Hillcrest Medical Research | DeLand | Florida | 32720 | — |
| Universal Axon Clinical Research, LLC | Doral | Florida | 33166 | — |
| Suncoast Research Associates | Doral | Florida | 33172 | — |
| AMR Clinical | Fort Myers | Florida | 33912 | — |
| Robert B. Pritt, DO | Fort Myers | Florida | 33912 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | — |
| Las Mercedes Medical Research | Hialeah | Florida | 33012 | — |
| Research Centers of America | Hollywood | Florida | 33024 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Health Awareness, LLC | Jupiter | Florida | 33458 | — |
| M3 Wake Research - Lake City | Lake City | Florida | 32055 | — |
| SRA Trials North | Lauderdale Lakes | Florida | 33313 | — |
| Accel Research Sites - Maitland Clinical Research Unit | Maitland | Florida | 32751 | — |
| South Florida Research Organization | Medley | Florida | 33166 | — |
| Optimal Research | Melbourne | Florida | 32934 | — |
| Flourish Research - Miami, LLC | Miami | Florida | 33135 | — |
| Florida Pharmaceutical Research & Associates, Inc. | Miami | Florida | 33143 | — |
| Nuren Medical and Research Center | Miami | Florida | 33144 | — |
| Advanced Clinical Research - Miami - Southwest 92nd Street | Miami | Florida | 33156 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| IMIC Medical Research | Miami | Florida | 33176 | — |
| Miami Dade Medical Research Institute, LLC | Miami | Florida | 33176 | — |
| Pioneer Clinical Studies | Miami | Florida | 33176 | — |
| 3Sync Research | Miami Lakes | Florida | 33014 | — |
| Palm Springs Community Health Center | Miami Lakes | Florida | 33014 | — |
| Angels Clinical Research Institute | Miami Lakes | Florida | 33016 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | — |
| Headlands Research Orlando | Orlando | Florida | 32806 | — |
| 3Sync Research | Palm Springs | Florida | 33461 | — |
| Innovation Medical Research Center | Palmetto Bay | Florida | 33157 | — |
| Tropical Clinical Trials | Palmetto Bay | Florida | 33176 | — |
| Suncoast Research Associates | Pembroke Pines | Florida | 33024 | — |
| DBC Research USA | Pembroke Pines | Florida | 33029 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| GCP Research, Global Clinical professionals | St. Petersburg | Florida | 33705 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| Angels Clinical Research Institute | Tampa | Florida | 33614 | — |
| Santos Research Center | Tampa | Florida | 33615 | — |
| Synexus Clinical Research US, Inc. | The Villages | Florida | 32162 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| M3 Wake Research - Atlanta | Atlanta | Georgia | 30328 | — |
| DelRicht Research | Atlanta | Georgia | 30329 | — |
| AGILE Clinical Research Trials, LLC | Sandy Springs | Georgia | 30328 | — |
| Javara - Privia Medical Group Georgia - Savannah | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Chicago Clinical Research Institute Inc. | Chicago | Illinois | 60607 | — |
| DM Clinical Research - Chicago | Melrose Park | Illinois | 60160 | — |
| Koch Family Medicine | Morton | Illinois | 61550 | — |
| Accellacare - DuPage | Oak Lawn | Illinois | 60453 | — |
| The South Bend Clinic /Avacare | South Bend | Indiana | 46617 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Velocity Clinical Research, Sioux City | Sioux City | Iowa | 51106 | — |
| AMR Clinical | El Dorado | Kansas | 67042 | — |
| Johnson County Clinical Trials | Lenexa | Kansas | 66219 | — |
| AMR Clinical | Newton | Kansas | 67114 | — |
| Tekton Research, LLC. | Wichita | Kansas | 67218 | — |
| AMR Clinical | Wichita | Kansas | 67226 | — |
| AMR Clinical | Lexington | Kentucky | 40509 | — |
| DelRicht Research | New Orleans | Louisiana | 70115 | — |
| Velocity Clinical Research - New Orleans | New Orleans | Louisiana | 70119 | — |
| Pharmaron | Baltimore | Maryland | 21201 | — |
| Velocity Clinical Research, Rockville | Rockville | Maryland | 20854 | — |
| DM Clinical Research - Boston | Brookline | Massachusetts | 02446 | — |
| Walgreens Clinical Trials - Malden, MA | Malden | Massachusetts | 02148 | — |
| ActivMed Practices and Research | Methuen | Massachusetts | 01844 | — |
| Henry Ford St. John Hospital | Grosse Pointe Woods | Michigan | 48236 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| Revival Research Institute, LLC | Southfield | Michigan | 48075 | — |
| DM Clinical Research - Detroit | Southfield | Michigan | 48076 | — |
| Clinical Research Institute | Minneapolis | Minnesota | 55402 | — |
| Velocity Clinical Research, Gulfport | Gulfport | Mississippi | 39503 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Sundance Clinical Research, LLC | St Louis | Missouri | 63141 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Velocity Clinical Research, Grand Island | Grand Island | Nebraska | 68803 | — |
| Be Well Clinical Studies - Lincoln | Lincoln | Nebraska | 68516 | — |
| Velocity Clinical Research, Norfolk | Norfolk | Nebraska | 68701 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| M3 Wake Research - Las Vegas Wellness Way | Las Vegas | Nevada | 89106 | — |
| DM Clinical Research - Jersey City | Jersey City | New Jersey | 07306 | — |
| Albuquerque Clinical Trials, Inc. | Albuquerque | New Mexico | 87102 | — |
| DM Clinical Research - Albuquerque | Albuquerque | New Mexico | 87106 | — |
| AXCES Research Group, LLC | Santa Fe | New Mexico | 87505 | — |
| Drug Trials America | Hartsdale | New York | 10530 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Accellacare - Cary | Cary | North Carolina | 27518 | — |
| Javara - Tryon Medical Partners | Charlotte | North Carolina | 28210 | — |
| Duke Vaccine and Trials Unit | Durham | North Carolina | 27703 | — |
| Accellacare - Hickory | Hickory | North Carolina | 28601 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Centricity Research New Bern Multispecialty | New Bern | North Carolina | 28562 | — |
| Eximia Research - NC, LLC | Raleigh | North Carolina | 27607 | — |
| Accellacare - Raleigh | Raleigh | North Carolina | 27609 | — |
| M3 Wake Research, Inc. | Raleigh | North Carolina | 27612 | — |
| Accellacare - Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Accellacare - Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare - Piedmont | Statesville | North Carolina | 28625 | — |
| Trial Management Associates - Wilmington - Floral Parkway | Wilmington | North Carolina | 28403 | — |
| Accellacare - Winston-Salem | Winston-Salem | North Carolina | 27103 | — |
| Wake Forest Baptist Health | Winston-Salem | North Carolina | 27157 | — |
| Cincinnati Children's Hospital Medical Center Vaccine Research Center | Cincinnati | Ohio | 45206 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| Epic Medical Research - Chickasha | Chickasha | Oklahoma | 73018 | — |
| Tekton Research, LLC. | Edmond | Oklahoma | 73013 | — |
| Tekton Research, LLC. | Moore | Oklahoma | 73160 | — |
| AMR Clinical | Norman | Oklahoma | 73069 | — |
| Tekton Research, LLC. | Yukon | Oklahoma | 73099 | — |
| Velocity Clinical Research, Medford | Medford | Oregon | 97504 | — |
| Central Erie Primary Care | Erie | Pennsylvania | 16508 | — |
| Velocity Clinical Research, Providence | East Greenwich | Rhode Island | 02818 | — |
| TMA Headlands LLC (d/b/a Trial Management Associates) | Myrtle Beach | South Carolina | 29572 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| M3 Wake Research - Chattanooga | Chattanooga | Tennessee | 37421 | — |
| AMR Clinical | Knoxville | Tennessee | 37909 | — |
| Accellacare US Inc., d/b/a Accellacare of Knoxville | Knoxville | Tennessee | 37912 | — |
| Elligo Clinical Research Center | Austin | Texas | 78704 | — |
| Orion Clinical Research | Austin | Texas | 78759 | — |
| Velocity Clinical Research, Austin | Austin | Texas | 78759 | — |
| Headlands Horizons, LLC dba Headlands Research-Brownsville | Brownsville | Texas | 78526 | — |
| Epic Medical Research - Carrollton | Carrollton | Texas | 75006 | — |
| Lonestar Clinical Research - Dallas | Dallas | Texas | 75243 | — |
| Headlands Research-El Paso | El Paso | Texas | 79902 | — |
| Cedar Health Research - Euless | Euless | Texas | 76040 | — |
| Mercury Clinical Research (Administrative Office - Archival Purposes) | Houston | Texas | 77054 | — |
| DM Clinical Research- Cyfair | Houston | Texas | 77065 | — |
| DM Clinical Research - Bellaire | Houston | Texas | 77081 | — |
| Mercury Clinical Research - Santa Clara Family Clinic | Houston | Texas | 77087 | — |
| DM Clinical Research - Dallas | Irving | Texas | 75061 | — |
| SMS Clinical Research | Mesquite | Texas | 75149 | — |
| Epic Medical Research - Mesquite | Mesquite | Texas | 75150 | — |
| LinQ Research | Pearland | Texas | 77584 | — |
| ACRC Trials | Plano | Texas | 75024 | — |
| ACRC Trials | Plano | Texas | 75093 | — |
| Avacare | San Angelo | Texas | 76903 | — |
| IMA Clinical Research San Antonio | San Antonio | Texas | 78229 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| DM Clinical Research - Sugar Land | Sugar Land | Texas | 77478 | — |
| Sugar Lakes Family Practice, PA | Sugar Land | Texas | 77479 | — |
| Dynamed Clinical Research, LP d/b/a DM Clinical Research | Tomball | Texas | 77375 | — |
| Cope Family Medicine / Avacare | Bountiful | Utah | 84010 | — |
| J. Lewis Research, Inc. / Foothill Family Clinic Draper | Draper | Utah | 84020 | — |
| J. Lewis Research, Inc. / Foothill Family Clinic | Salt Lake City | Utah | 84109 | — |
| J. Lewis Research, Inc. / Foothill Family Clinic South | Salt Lake City | Utah | 84121 | — |
| Velocity Clinical Research, Salt Lake City | West Jordan | Utah | 84088 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| AMR Clinical | Norfolk | Virginia | 23502 | — |
| Tidewater Clinical Research, LLC | Norfolk | Virginia | 23502 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23226 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07300839, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced Apr 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07300839 live on ClinicalTrials.gov.