ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
Public ClinicalTrials.gov record NCT07301255. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 12-Week Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of ENV-294 in Adult Participants With Moderate-to-Severe Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and potential efficacy of ENV-294 in adults with moderate to severe asthma who are receiving background treatment with inhaled corticosteroids (ICS) and long-acting beta₂-agonists (LABA). Participants will take oral ENV-294 or placebo once daily for 12 weeks. The study includes a screening period of up to 28 days before randomization to confirm eligibility. Study visits and assessments will be conducted to monitor safety, measure drug levels in the blood, and evaluate effects on asthma control and lung function.
Study identification
- NCT ID
- NCT07301255
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 50 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 8, 2026
- Primary completion
- Nov 30, 2026
- Completion
- Dec 31, 2026
- Last update posted
- Jul 28, 2026
2026 – 2027
United States locations
- U.S. sites
- 18
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Enveda Investigative Site | Birmingham | Alabama | 35209 | Recruiting |
| Enveda Investigative Site | Los Angeles | California | 90025 | Recruiting |
| Enveda Investigative Site | San Jose | California | 95117 | Recruiting |
| Enveda Investigative Site | West Hills | California | 91307 | Recruiting |
| Enveda Investigative Site | Colorado Springs | Colorado | 80907 | Recruiting |
| Enveda Investigative Site | Hialeah | Florida | 33012 | Recruiting |
| Enveda Investigative Site | Miami | Florida | 33135 | Recruiting |
| Enveda Investigative Site | Albany | Georgia | 31707 | Recruiting |
| Enveda Investigative Site | Maryville | Illinois | 62062 | Recruiting |
| Enveda Investigative Site | Kansas City | Kansas | 66160 | Recruiting |
| Enveda Investigative Site | Owensboro | Kentucky | 42301 | Recruiting |
| Enveda Investigative Site | Southfield | Michigan | 48075 | Recruiting |
| Enveda Investigative Site | St Louis | Missouri | 63141 | Recruiting |
| Enveda Investigative Site | Clackamas | Oregon | 97015 | Recruiting |
| Enveda Investigative Site | Medford | Oregon | 97504 | Recruiting |
| Enveda Investigative Site | North Charleston | South Carolina | 29406 | Recruiting |
| Enveda Investigative Site | McKinney | Texas | 75069 | Recruiting |
| Enveda Investigative Site | Madison | Wisconsin | 53792 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07301255, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2026 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07301255 live on ClinicalTrials.gov.