Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
Public ClinicalTrials.gov record NCT07321912. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II Open Label Basket Trial Study Using Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
Study identification
- NCT ID
- NCT07321912
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Enrollment
- 406 participants
Conditions and interventions
Conditions
Interventions
- Eflornithine Drug
- Topotecan Drug
- Cyclophosphamide Drug
- Vincristine Drug
- Doxorubicin Drug
- Ifosfamide Drug
- Etoposide Drug
- Cisplatin Drug
- Methotrexate Drug
Drug
Eligibility (public fields only)
- Age range
- 0 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2026
- Primary completion
- May 31, 2031
- Completion
- May 31, 2036
- Last update posted
- Jul 8, 2026
2026 – 2036
United States locations
- U.S. sites
- 2
- U.S. states
- 2
- U.S. cities
- 2
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Children's Hospital | Tampa | Florida | 33614 | Recruiting |
| Penn State Milton S. Hershey Medical Center and Children's Hospital | Hershey | Pennsylvania | 17033 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07321912, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 8, 2026 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07321912 live on ClinicalTrials.gov.