Phase 2 Study of Kylo-11 in ASCVD Patients With Elevated Lp(a)
Public ClinicalTrials.gov record NCT07327840. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled Phase 2 Study to Evaluate Efficacy and Safety of Kylo-11 in Participants With Atherosclerotic Cardiovascular Disease and Elevated Lipoprotein(a)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2, double-blind, randomized, placebo-controlled, multi-center, dose-finding study to evaluate the efficacy and safety of Kylo-11 administered subcutaneously compared to placebo in participants with ASCVD and elevated Lp(a).
Study identification
- NCT ID
- NCT07327840
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 204 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 29, 2025 (Actual)
- Primary completion
- Sep 30, 2026 (Actual)
- Completion
- Aug 31, 2028 (Estimated)
- Last update posted
- Oct 16, 2026
2025 – 2028
United States locations
- U.S. sites
- 16
- U.S. states
- 6
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alliance Clinical - Los Angeles | Los Angeles | California | 90301 | — |
| Alliance Clinical - San Diego | San Diego | California | 92115 | — |
| FOMAT - Comprehensive Cardiovascular Care-Santa Maria California | Santa Maria | California | 93454 | — |
| Excel Medical Trials - Flourish Research | Boca Raton | Florida | 33434 | — |
| Clinical Research of West Florida (CRWF) - Clearwater | Clearwater | Florida | 33765 | — |
| Arrow Clinical Trials LLC | Daytona Beach | Florida | 32117 | — |
| Family Research and Healthcare Center Inc. | Doral | Florida | 33126 | — |
| Family Research Centers - Hialeah | Hialeah | Florida | 33012 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Universal Axon Clinical Research | Miami | Florida | 33166 | — |
| Clinical Research of West Florida (CRWF) - Tampa | Tampa | Florida | 33606 | — |
| Emory Healthcare-Emory Heart & Vascular Center - Executive Park | Atlanta | Georgia | 30324 | — |
| Centricity Research - Columbus | Columbus | Georgia | 31904 | — |
| Care Access-Lake Charles, LA | Lake Charles | Louisiana | 70601 | — |
| Alliance Clinical Las Vegas Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Centricity Research d/b/a Lucas Research, Inc. | Morehead City | North Carolina | 28557 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 43 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07327840, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07327840 live on ClinicalTrials.gov.