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Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Modes of Influenza Transmission 2b Baseline SAR

ClinicalTrials.gov ID: NCT07342556

Public ClinicalTrials.gov record NCT07342556. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 5, 2026, 6:32 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

EMIT-2b: Evaluating Modes of Influenza Transmission Through the Conduct of Controlled Human Influenza Virus Infection Transmission Trials (CHIVITTs)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a research study to investigate how influenza transmits from person-to-person. Participation as a healthy "Recipient" in this study involves: * Home semi-quarantine lasting about 14 days during which the participants must wear an N95 in class and take other precautions * Daily assessments and clinic visits for 14 days * Spending every weekday evening for about 14 days from around 6 - 10 pm, including a provided dinner, in a controlled environment. There may be additional sessions and different required participation times on weekends * Exposure to people infected with influenza in the controlled environment * Three blood draws, at the start, at the end of 14 days, and about a month after the end. * A follow-up clinic visits one month after the end of home semi-quarantine * A two-month follow-up phone call. This study may increase the participant's risk of catching influenza. If the participants get infected during the study, the investigators may: * Provide the participants with a prescription for antiviral medication or * Refer the participants for medical care * Ask the participants to become a Donor and expose other Recipients. The participants will be compensated for their time and active participation in the study; however, they may not personally benefit from the study. While the participants may receive supportive care for an infection resulting from the study, this is not meant to replace their regular medical care. If the participants become very ill and need referral for medical care, they or their medical insurance will be billed. If the participants are someone who recently became infected with influenza either through their daily activities or by participating in this study as a Recipient, they are invited to participate in this research study as a Donor and interact with a group of health participants in a controlled environment. Participation in this study as a Donor involves exposing Recipients for at least one and up to five days including: * Attend exposure events in a controlled environment * Weekday evenings from around 6-10 pm * Additional day and evening events on weekends * Events include a provided dinner * Daily assessments and clinic visits for 1 to 5 days * Provide exhaled breath samples for 30 to 60 minutes * Three blood draws, at the start and end of exposure events, and about a month after the end * A follow-up clinic visit one month after their last exposure event * A two-month follow-up phone call If the participants experience severe symptoms related to their influenza infection, we may: * Provide the participants with a prescription for antiviral medication or * Refer the participants for medical care The participants will be compensated for their time and active participation in the study; however, they may not personally benefit from the study. While the participants may receive supportive care for their influenza infection, this is not meant to replace their regular medical care. If the participants become very ill and need referral for medical care, they or their medical insurance will be billed.

Study identification

NCT ID
NCT07342556
Recruitment status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Enrollment
80 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 49 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 31, 2025
Primary completion
Feb 28, 2026
Completion
Apr 30, 2026
Last update posted
Jan 14, 2026

2026

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
University of Maryland College Park Maryland 20742

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07342556, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 14, 2026 · Synced Sep 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07342556 live on ClinicalTrials.gov.

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