PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
Public ClinicalTrials.gov record NCT07355296. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PODOMOUNT-Basket, a Phase II, Multicentre, Randomised, 2-arm Parallel-group, Double-blind, Placebo-controlled Basket Trial to Assess Safety, Tolerability, PK, and Efficacy of BI 764198 in Four Proteinuric Kidney Diseases
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resistant primary minimal change disease (TR-pMCD), Alport Syndrome (AS), and treatment-resistant primary membranous nephropathy (TR-pMN). Adolescents with treatment-resistant primary MCD can also participate in this study. The purpose of this study is to find out whether a medicine called BI 764198 helps people with these kidney conditions. Participants are put into 2 groups randomly, which means by chance. One group takes BI 764198 tablets, and the other group takes placebo tablets. Placebo tablets look like BI 764198 tablets but do not contain any medicine. Participants take a tablet once a day for 20 weeks. All participants also continue their standard medication for their kidney condition during the study. Participants have twice the chance of being placed in the BI 764198 group than in the placebo group. Participants are in the study for about 7 months. During this time, they visit the study site 6 times and have 3 phone calls. Doctors regularly test the protein levels in participants' urine by collecting urine samples. They also check kidney function by taking blood samples. The results are compared between the two groups to see whether the treatment works. The doctors also regularly check participants' health and take note of any unwanted effects.
Study identification
- NCT ID
- NCT07355296
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 132 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2026
- Primary completion
- Jan 19, 2028
- Completion
- Feb 16, 2028
- Last update posted
- Sep 1, 2026
2026 – 2028
United States locations
- U.S. sites
- 26
- U.S. states
- 14
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Nephrology Consultants, LLC | Huntsville | Alabama | 35805 | Recruiting |
| Kidney Disease Medical Group | Glendale | California | 91206 | Recruiting |
| Amicis Research Center - Balboa | Granada Hills | California | 91344 | Recruiting |
| Academic Medical Research Institute - Glendale | Los Angeles | California | 90022 | Recruiting |
| University of California Los Angeles | Los Angeles | California | 90095 | Not yet recruiting |
| Colorado Kidney Care | Denver | Colorado | 80220 | Recruiting |
| Florida Kidney Physicians - Boca Raton | Boca Raton | Florida | 33487 | Recruiting |
| Florida Kidney Physicians, LLC - Fort Lauderdale | Fort Lauderdale | Florida | 33316 | Recruiting |
| Total Research Group, LLC | Miami | Florida | 33126 | Recruiting |
| CTR Oakwater, LLC | Orlando | Florida | 32806 | Recruiting |
| Florida Kidney Physicians - Riverview/Brandon | Riverview | Florida | 33578 | Recruiting |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | Not yet recruiting |
| Endeavor Health | Evanston | Illinois | 60201 | Not yet recruiting |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | Not yet recruiting |
| St. Clair Nephrology Research, LLC - Shelby Township | Shelby | Michigan | 48315 | Recruiting |
| New York Nephrology and Dialysis Access Surgery, PC | Clifton Park | New York | 12065 | Recruiting |
| Queens Long Island Kidney Center | Fresh Meadows | New York | 11366 | Not yet recruiting |
| NYU Langone Nephrology Associates-Mineola | Mineola | New York | 11501 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Not yet recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Not yet recruiting |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Not yet recruiting |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | Not yet recruiting |
| Southeast Renal Research Institute | Chattanooga | Tennessee | 37404 | Recruiting |
| Nephrotex Research Group | Dallas | Texas | 75231 | Not yet recruiting |
| Provecta Researh Network | Houston | Texas | 77027 | Recruiting |
| West Virginia University Medicine | Morgantown | West Virginia | 26506 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 137 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07355296, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 1, 2026 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07355296 live on ClinicalTrials.gov.