A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.
Public ClinicalTrials.gov record NCT07356453. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors With BRCA1/2 Mutations or Other DDR Deficiencies or High Replication Stress.
Study identification
- NCT ID
- NCT07356453
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- FoRx Therapeutics AG
- Industry
- Enrollment
- 40 participants
Conditions and interventions
Conditions
Interventions
- FORX-428 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2025
- Primary completion
- May 31, 2027
- Completion
- Mar 31, 2028
- Last update posted
- Jan 20, 2026
2025 – 2028
United States locations
- U.S. sites
- 8
- U.S. states
- 6
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Stanford University Medical Center | Palo Alto | California | 94304 | Recruiting |
| University of California, San Francisco | San Francisco | California | 94143 | Recruiting |
| START - Midwest | Grand Rapids | Michigan | 49546 | Recruiting |
| Washington University St. Louis | St Louis | Missouri | 63108 | Recruiting |
| Knight Cancer Institute | Portland | Oregon | 97239 | Recruiting |
| University of Texas - MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| START - San Antonio | San Antonio | Texas | 78229 | Recruiting |
| NEXT - Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07356453, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 20, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07356453 live on ClinicalTrials.gov.