Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
Public ClinicalTrials.gov record NCT07379827. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Effectiveness and Adverse-effect Switch Evaluation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to describe real-world treatment patterns, effectiveness and adverse events of adults diagnosed with schizophrenia that have initiated xanomeline and trospium chloride (KarXT) treatment in the United States
Study identification
- NCT ID
- NCT07379827
- Recruitment status
- Recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 1,500 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 25, 2026
- Primary completion
- Jun 19, 2028
- Completion
- Jun 19, 2028
- Last update posted
- Aug 18, 2026
2026 – 2028
United States locations
- U.S. sites
- 55
- U.S. states
- 17
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SanRo Clinical Research Group | Bryant | Arkansas | 72022 | Recruiting |
| Pamoja Advanced Nursing Practice | Anaheim | California | 92801 | Recruiting |
| Local Institution - 0003 | Anaheim | California | 92805 | Not yet recruiting |
| Inland Psychiatric Medical Group (IPMG)-Chino | Chino | California | 91710 | Recruiting |
| Local Institution - 0012 | La Palma | California | 90623 | Not yet recruiting |
| Local Institution - 0043 | Oceanside | California | 92056-4509 | Not yet recruiting |
| Local Institution - 0028 | Stanford | California | 94304 | Not yet recruiting |
| Envision Trials LLC | Bonita Springs | Florida | 34134 | Recruiting |
| Galiz Research | Hialeah | Florida | 33016-1814 | Recruiting |
| Local Institution - 0030 | Homestead | Florida | 33030 | Not yet recruiting |
| New Access Research & Medical Services Inc - Kendall | Kendall | Florida | 33186 | Recruiting |
| Local Institution - 0032 | Miami | Florida | 33015 | Not yet recruiting |
| Banyan Behavioal Care Program - CSU | Miami | Florida | 33134 | Recruiting |
| Local Institution - 0007 | Miami | Florida | 33155 | Not yet recruiting |
| BioResearch Partner - Miami | Miami | Florida | 33175 | Recruiting |
| Medical Research of Central Florida | Orange City | Florida | 32763 | Recruiting |
| Local Institution - 0040 | Orlando | Florida | 32803 | Not yet recruiting |
| Emory University. | Atlanta | Georgia | 30303 | Recruiting |
| Local Institution - 0049 | Austell | Georgia | 30106 | Not yet recruiting |
| Local Institution - 0044 | Marietta | Georgia | 30060 | Not yet recruiting |
| Local Institution - 0046 | Crystal Lake | Illinois | 60523 | Not yet recruiting |
| Amr Conventions Research - Illinois | Warrenville | Illinois | 60555 | Recruiting |
| Local Institution - 0014 | Bloomfield Township | Michigan | 48302-1909 | Not yet recruiting |
| Local Institution - 0036 | Detroit | Michigan | 48203 | Not yet recruiting |
| Local Institution - 0034 | Apple Valley | Minnesota | 55124 | Not yet recruiting |
| Local Institution - 0054 | Duluth | Minnesota | 55811 | Not yet recruiting |
| Local Institution - 0041 | Lincoln | Nebraska | 68526-9474 | Not yet recruiting |
| Local Institution - 0055 | Las Vegas | Nevada | 89146 | Not yet recruiting |
| Local Institution - 0037 | Buffalo | New York | 14215 | Not yet recruiting |
| Local Institution - 0004 | Monsey | New York | 10952 | Not yet recruiting |
| Local Institution - 0038 | Rochester | New York | 14623 | Not yet recruiting |
| Local Institution - 0020 | White Plains | New York | 10601 | Not yet recruiting |
| Magnolia Clinical Research, LLC | Cary | North Carolina | 27513 | Recruiting |
| PPD Virtual - PPD - US | Wilmington | North Carolina | 28401-3331 | Recruiting |
| Local Institution - 0031 | Mason | Ohio | 45040-7846 | Not yet recruiting |
| The Rivus Wellness & Research Institute | Oklahoma City | Oklahoma | 73112-8729 | Recruiting |
| Local Institution - 0052 | Tulsa | Oklahoma | 74135 | Not yet recruiting |
| Perelman School of Medicine at the University of Pennsylvania | Philadelphia | Pennsylvania | 19104-4238 | Recruiting |
| Local Institution - 0053 | State College | Pennsylvania | 16801 | Not yet recruiting |
| Local Institution - 0051 | Cordova | Tennessee | 38018 | Not yet recruiting |
| Psychiatric Consultants, Pc | Franklin | Tennessee | 37607 | Recruiting |
| Local Institution - 0016 | Austin | Texas | 78754 | Not yet recruiting |
| Local Institution - 0050 | Dallas | Texas | 75390 | Not yet recruiting |
| Local Institution - 0021 | Fort Worth | Texas | 76132 | Not yet recruiting |
| Local Institution - 0033 | Houston | Texas | 77007-9015 | Not yet recruiting |
| Local Institution - 0026 | Houston | Texas | 77008-1758 | Not yet recruiting |
| Local Institution - 0022 | Houston | Texas | 77054-2852 | Not yet recruiting |
| Local Institution - 0010 | Houston | Texas | 77054 | Not yet recruiting |
| Pioneer Research Solutions, Inc. | Houston | Texas | 77099 | Recruiting |
| Local Institution - 0017 | Irving | Texas | 75062-2757 | Not yet recruiting |
| Local Institution - 0013 | McKinney | Texas | 75092 | Not yet recruiting |
| Perceptive Pharma Research | Richmond | Texas | 77407-3498 | Recruiting |
| UT Health San Antonio - Behavioral Health and Wellness Center | San Antonio | Texas | 78240 | Recruiting |
| Local Institution - 0018 | Stafford | Texas | 77477-3954 | Not yet recruiting |
| Local Institution - 0045 | Petersburg | Virginia | 23805 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07379827, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 18, 2026 · Synced Sep 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07379827 live on ClinicalTrials.gov.