A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa
Public ClinicalTrials.gov record NCT07384975. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Multicenter, Randomized, Double-blind, Placebo-controlled Study of NAV-240 in Adult Participants With Moderate-to-Severe Hidradenitis Suppurativa
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objective of this study is to determine if NAV-240 works more effectively than a dummy treatment (placebo) for participants with moderate-to-severe HS. The main endpoint of this study is the percentage of participants achieving Hidradenitis Suppurativa Clinical Response (HiSCR) 75 at Week 16, meaning at least a 75% reduction in inflamed skin bumps (abscess and inflammatory nodule (AN) count) with no increase in number of abscesses or draining tunnels (channels under the skin that leak fluid or pus) compared to the baseline (start of the study). Participants will: * Receive NAV-240 dose 1, NAV-240 dose 2 or placebo as a drip into the veins (intravenous infusion). * Visit the clinic up to 9 times for checkups and tests over 22 weeks. * Complete a daily diary about their skin pain.
Study identification
- NCT ID
- NCT07384975
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 5, 2026 (Actual)
- Primary completion
- Sep 2027 (Estimated)
- Completion
- Oct 2027 (Estimated)
- Last update posted
- Jul 22, 2026
2026 – 2027
United States locations
- U.S. sites
- 14
- U.S. states
- 7
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Dermatology Specialist | Phoenix | Arizona | 85006 | Recruiting |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260 | Recruiting |
| Accel Research Sites Network | Maitland | Florida | 32751 | Recruiting |
| Floridian Research Institute | Miami | Florida | 33179 | Recruiting |
| Cordova Research Institute | Miami | Florida | 33182 | Recruiting |
| Ziaderm Research, LLC | North Miami Beach | Florida | 33162 | Recruiting |
| FWD Clinical Research | Tamarac | Florida | 33321 | Recruiting |
| MplusM - D&H Tamarac Research Center | Tamarac | Florida | 33321 | Recruiting |
| ForCare Clinical Research | Tampa | Florida | 33613 | Recruiting |
| Kentucky Advanced Medical Research LLC | Murray | Kentucky | 42071 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| SKY Integrative Medical Center | Ridgeland | Mississippi | 39157 | Recruiting |
| StracSkin, PLLC | Portsmouth | New Hampshire | 03801 | Recruiting |
| Equity Medical, LLC | The Bronx | New York | 10455 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 27 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07384975, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 22, 2026 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07384975 live on ClinicalTrials.gov.