A Study to Learn About mRNA Vaccines Against Influenza in Adults
Public ClinicalTrials.gov record NCT07431853. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, CLINICAL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF MRNA VACCINES AGAINST INFLUENZA IN ADULTS 18 YEARS OF AGE AND OLDER
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn about safety in participants taking the study vaccine (mRNA-based vaccine) and the ability of the study vaccine to trigger the body's immune response, targeting the flu virus (influenza virus). This study is seeking healthy participants 18 years of age or older. All participants in this study will receive only 1 dose in their arm, to deliver one of the experimental flu vaccines or one of the approved flu vaccines used for comparison. Participants will take part in this study for about 6 months, and participants will need to visit the study site at least 3 times. A blood sample will be taken at each of the 3 planned study visits and a swab from inside the nose will be taken at the first study visit.
Study identification
- NCT ID
- NCT07431853
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 770 participants
Conditions and interventions
Conditions
Interventions
- Vaccine Candidate #1 Biological
- Vaccine Candidate #2 Biological
- Vaccine Candidate #3 Biological
- Vaccine Candidate #4 Biological
- Vaccine Candidate #5 Biological
- Vaccine Candidate #6 Biological
- TIV1 or TIV2 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 22, 2026
- Primary completion
- Jun 21, 2027
- Completion
- Jun 21, 2027
- Last update posted
- May 5, 2026
2026 – 2027
United States locations
- U.S. sites
- 15
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AMR Clinical | Mobile | Alabama | 36608 | Recruiting |
| Diablo Clinical Research, LLC d/b/a Flourish Research | Walnut Creek | California | 94598 | Recruiting |
| Clinical Research Consulting, LLC | Milford | Connecticut | 06460 | Recruiting |
| George Washington Medical Faculty Associates | Washington D.C. | District of Columbia | 20037 | Recruiting |
| Indago Research & Health Center, Inc | Hialeah | Florida | 33012 | Recruiting |
| Palm Springs Community Health Center | Miami Lakes | Florida | 33014 | Recruiting |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | Recruiting |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | Recruiting |
| AMR Clinical | Kansas City | Missouri | 64114 | Recruiting |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | Recruiting |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | Recruiting |
| SMS Clinical Research LLC | Mesquite | Texas | 75149 | Recruiting |
| DM Clinical Research | Tomball | Texas | 77375 | Recruiting |
| J. Lewis Research, Inc. / Foothill Family Clinic | Salt Lake City | Utah | 84109 | Recruiting |
| Charlottesville Medical Research Center, LLC | Charlottesville | Virginia | 22911 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07431853, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07431853 live on ClinicalTrials.gov.