Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis
Public ClinicalTrials.gov record NCT07474792. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-Blinded, Placebo- Controlled, Dose-Range Finding Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of ORKA-002 in Participants With Moderate-to-Severe Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-002 in adult participants with moderate-to-severe plaque psoriasis.
Study identification
- NCT ID
- NCT07474792
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 160 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 19, 2026 (Actual)
- Primary completion
- Oct 2027 (Estimated)
- Completion
- Apr 2029 (Estimated)
- Last update posted
- Oct 16, 2026
2026 – 2029
United States locations
- U.S. sites
- 29
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Oruka Therapeutics Investigative Site | Birmingham | Alabama | 35203 | — |
| Oruka Therapeutics Investigative Site | Phoenix | Arizona | 85032 | — |
| Oruka Therapeutics Investigative Site | Fountain Valley | California | 92708 | — |
| Oruka Therapeutics Investigative Site | Los Angeles | California | 90045 | — |
| Oruka Therapeutics Investigative Site | San Diego | California | 92123 | — |
| Oruka Therapeutics Investigative Site | Santa Ana | California | 92701 | — |
| Oruka Therapeutics Investigative Site | Santa Monica | California | 90403 | — |
| Oruka Therapeutics Investigative Site | Cromwell | Connecticut | 06416 | — |
| Oruka Therapeutics Investigative Site | Miami | Florida | 33124 | — |
| Oruka Therapeutics Investigative Site | Rolling Meadows | Illinois | 60008 | — |
| Oruka Therapeutics Investigative Site | Boston | Massachusetts | 02115 | — |
| Oruka Therapeutics Investigative Site | Milford | Massachusetts | 01757 | — |
| Oruka Therapeutics Investigative Site | Ann Arbor | Michigan | 48109 | — |
| Oruka Therapeutics Investigative Site | Detroit | Michigan | 48202 | — |
| Oruka Therapeutics Investigative Site | Warren | Michigan | 48088 | — |
| Oruka Therapeutics Investigative Site | New Brighton | Minnesota | 55112 | — |
| Oruka Therapeutics Investigative Site | Omaha | Nebraska | 68144 | — |
| Oruka Therapeutics Investigative Site | Elmhurst | New York | 11373 | — |
| Oruka Therapeutics Investigative Site | New York | New York | 10029 | — |
| Oruka Therapeutics Investigative Site | Wilmington | North Carolina | 28405 | — |
| Oruka Therapeutics Investigative Site | Bexley | Ohio | 43209 | — |
| Oruka Therapeutics Investigative Site | Portland | Oregon | 97201 | — |
| Oruka Therapeutics Investigative Site | Warrenton | Oregon | 97146 | — |
| Oruka Therapeutics Investigative Site | Charleston | South Carolina | 29407 | — |
| Oruka Therapeutics Investigative Site | Dallas | Texas | 75231 | — |
| Oruka Therapeutics Investigative Site | Dallas | Texas | 75390 | — |
| Oruka Therapeutics Investigative Site | Houston | Texas | 77004 | — |
| Oruka Therapeutics Investigative Site | Webster | Texas | 77598 | — |
| Oruka Therapeutics Investigative Site | Mill Creek | Washington | 98012 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07474792, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2026 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07474792 live on ClinicalTrials.gov.