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Recruiting Phase 2 Interventional

Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis

ClinicalTrials.gov ID: NCT07474792

Public ClinicalTrials.gov record NCT07474792. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 10, 2026, 1:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-Blinded, Placebo- Controlled, Dose-Range Finding Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of ORKA-002 in Participants With Moderate-to-Severe Plaque Psoriasis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multicenter, randomized, double-blinded, placebo-controlled, dose-range finding study to evaluate the efficacy and safety of ORKA-002 in adult participants with moderate-to-severe plaque psoriasis.

Study identification

NCT ID
NCT07474792
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Oruka Therapeutics, Inc.
Industry
Enrollment
160 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years to 79 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 18, 2026
Primary completion
Sep 30, 2027
Completion
Mar 31, 2029
Last update posted
Aug 9, 2026

2026 – 2029

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
28
Facility City State ZIP Site status
Oruka Therapeutics Investigative Site Birmingham Alabama 35203 Recruiting
Oruka Therapeutics Investigative Site Phoenix Arizona 85032 Recruiting
Oruka Therapeutics Investigative Site Fountain Valley California 92708 Recruiting
Oruka Therapeutics Investigative Site Los Angeles California 90045 Recruiting
Oruka Therapeutics Investigative Site San Diego California 92123 Recruiting
Oruka Therapeutics Investigative Site Santa Ana California 92701 Recruiting
Oruka Therapeutics Investigative Site Santa Monica California 90403 Recruiting
Oruka Therapeutics Investigative Site Cromwell Connecticut 06416 Recruiting
Oruka Therapeutics Investigative Site Miami Florida 33124 Recruiting
Oruka Therapeutics Investigative Site Rolling Meadows Illinois 60008 Recruiting
Oruka Therapeutics Investigative Site Boston Massachusetts 02115 Recruiting
Oruka Therapeutics Investigative Site Milford Massachusetts 01757 Recruiting
Oruka Therapeutics Investigative Site Ann Arbor Michigan 48109 Recruiting
Oruka Therapeutics Investigative Site Detroit Michigan 48202 Recruiting
Oruka Therapeutics Investigative Site Warren Michigan 48088 Recruiting
Oruka Therapeutics Investigative Site New Brighton Minnesota 55112 Recruiting
Oruka Therapeutics Investigative Site Omaha Nebraska 68144 Recruiting
Oruka Therapeutics Investigative Site Elmhurst New York 11373 Recruiting
Oruka Therapeutics Investigative Site New York New York 10029 Recruiting
Oruka Therapeutics Investigative Site Wilmington North Carolina 28405 Recruiting
Oruka Therapeutics Investigative Site Bexley Ohio 43209 Recruiting
Oruka Therapeutics Investigative Site Portland Oregon 97201 Recruiting
Oruka Therapeutics Investigative Site Warrenton Oregon 97146 Recruiting
Oruka Therapeutics Investigative Site Charleston South Carolina 29407 Recruiting
Oruka Therapeutics Investigative Site Dallas Texas 75231 Recruiting
Oruka Therapeutics Investigative Site Dallas Texas 75390 Recruiting
Oruka Therapeutics Investigative Site Houston Texas 77004 Recruiting
Oruka Therapeutics Investigative Site Webster Texas 77598 Recruiting
Oruka Therapeutics Investigative Site Mill Creek Washington 98012 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07474792, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 9, 2026 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07474792 live on ClinicalTrials.gov.

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