A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
Public ClinicalTrials.gov record NCT07477704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-Label, Dose-Ranging Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Weekly Alirocumab in Adults With Hypercholesterolemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels). The aim of the study is to see how safe and effective alirocumab is when given weekly to adult participants who have hypercholesterolemia. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug once a week * How much study drug is in the blood at different times
Study identification
- NCT ID
- NCT07477704
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 438 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 17, 2026 (Actual)
- Primary completion
- Dec 29, 2026 (Estimated)
- Completion
- Feb 23, 2027 (Estimated)
- Last update posted
- Oct 15, 2026
2026 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| Anaheim Clinical Trials | Anaheim | California | 92801 | — |
| Cenexel CNS | Los Alamitos | California | 90720 | — |
| Diablo Clinical Research - Flourish Research | Walnut Creek | California | 94598 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| Southwest General Healthcare Center | Fort Myers | Florida | 33907 | — |
| Precision Clinical Research | Sunrise | Florida | 33351 | — |
| K2 Medical Research The Villages | The Villages | Florida | 32159 | — |
| Center for Advanced Research and Education | Gainesville | Georgia | 30501 | — |
| Balanced Life Health Care Solutions | Lawrenceville | Georgia | 30046 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Velocity Clinical Research - Omaha | Omaha | Nebraska | 68134 | — |
| Palm Research Center, Mountainview Medical Center | Las Vegas | Nevada | 89128 | — |
| Velocity Clinical Research - Durham | Durham | North Carolina | 27701 | — |
| Accellacare of Wilmington | Wilmington | North Carolina | 28401 | — |
| Ohio Clinical Trials | Columbus | Ohio | 43212 | — |
| AMR Norman | Norman | Oklahoma | 73069 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Velocity Clinical Research, Medford | Medford | Oregon | 97504 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Tribe Clinical Research | Greenville | South Carolina | 29607 | — |
| Coastal Carolina Research Center_North Charleston | North Charleston | South Carolina | 29405 | — |
| Velocity Clinical Research Dallas | Dallas | Texas | 75230 | — |
| Valley Institute of Research, Rockwood Medical Clinic | Fort Worth | Texas | 76164 | — |
| Be Well Clinical Studies - Round Rock | Round Rock | Texas | 78681 | — |
| Flourish Research, Legacy Oaks Tower | San Antonio | Texas | 78229 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Charlottesville Medical Research | Charlottesville | Virginia | 22911 | — |
| Rainier Clinical Research Center | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07477704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07477704 live on ClinicalTrials.gov.