Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
Public ClinicalTrials.gov record NCT07497880. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to determine the efficacy of oral KAI-7535 once daily compared with placebo on percent change in body weight in participants living with obesity or overweight, with at least 1 weight-related comorbidity, without diabetes mellitus. Safety and tolerability and other weight-related outcomes will also be evaluated.
Study identification
- NCT ID
- NCT07497880
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 306 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 6, 2026 (Actual)
- Primary completion
- Jul 7, 2027 (Estimated)
- Completion
- Jul 7, 2027 (Estimated)
- Last update posted
- Sep 9, 2026
2026 – 2027
United States locations
- U.S. sites
- 31
- U.S. states
- 14
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kailera Clinical Site | Chandler | Arizona | 85225 | — |
| Kailera Clinical Site | Phoenix | Arizona | 85044 | — |
| Kailera Clinical Site | Irvine | California | 92614 | — |
| Kailera Clinical Site | Lincoln | California | 95648 | — |
| Kailera Clinical Site | Northridge | California | 91325 | — |
| Kailera Clinical Site | Hamden | Connecticut | 06517 | — |
| Kailera Clinical Site | Jacksonville | Florida | 32256 | — |
| Kailera Clinical Site | Jupiter | Florida | 33458 | — |
| Kailera Clinical Site | Palm Springs | Florida | 33461 | — |
| Kailera Clinical Site | Pembroke Pines | Florida | 33024 | — |
| Kailera Clinical Site | Decatur | Georgia | 30030 | — |
| Kailera Clinical Site | Chicago | Illinois | 60640 | — |
| Kailera Clinical Site | Skokie | Illinois | 60077 | — |
| Kailera Clinical Site | South Bend | Indiana | 46617 | — |
| Kailera Clinical Site | Kenner | Louisiana | 70065 | — |
| Kailera Clinical Site | Garden City | Michigan | 48135 | — |
| Kailera Clinical Site | Jefferson City | Missouri | 65109 | — |
| Kailera Clinical Site | Kansas City | Missouri | 64151 | — |
| Kailera Clinical Site | Spartanburg | South Carolina | 29303 | — |
| Kailera Clinical Site | Knoxville | Tennessee | 37909 | — |
| Kailera Clinical Site | Austin | Texas | 78705 | — |
| Kailera Clinical Site | Austin | Texas | 78757 | — |
| Kailera Clinical Site | Brownsville | Texas | 78520 | — |
| Kailera Clinical Site | Farmers Branch | Texas | 75234 | — |
| Kailera Clinical Site | Fort Worth | Texas | 76135 | — |
| Kailera Clinical Site | Mesquite | Texas | 75149 | — |
| Kailera Clinical Site | San Antonio | Texas | 78222 | — |
| Kailera Clinical Site | San Antonio | Texas | 78229 | — |
| Kailera Clinical Site | San Antonio | Texas | 78240 | — |
| Kailera Clinical Site | Sugar Land | Texas | 77479 | — |
| Kailera Clinical Site | Sandy City | Utah | 84093 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07497880, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2026 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07497880 live on ClinicalTrials.gov.