A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

ClinicalTrials.gov ID: NCT07501702

Public ClinicalTrials.gov record NCT07501702. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 8, 2026, 9:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With a Long-term Extension of Povetacicept in Adults With Generalized Myasthenia Gravis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the pharmacodynamic (PD) effect, safety, and tolerability of Povetacicept in participants with generalized myasthenia gravis (gMG).

Study identification

NCT ID: NCT07501702
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Vertex Pharmaceuticals Incorporated; Industry
Enrollment: 30 participants

Conditions and interventions

Conditions

Myasthenia Gravis, Generalized

Interventions

Povetacicept Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 12, 2026
Primary completion: Mar 1, 2029
Completion: Mar 1, 2029
Last update posted: Sep 3, 2026

2026 – 2029

United States locations

U.S. sites: 15
U.S. states: 8
U.S. cities: 13

Facility	City	State	ZIP	Site status
Tri Valley Neurology Medical Associates Inc.	Mission Hills	California	91345	Recruiting
Neurology Offices	Boca Raton	Florida	33428	Recruiting
SFM Clinical Reseach, LLC	Boca Raton	Florida	33487	Recruiting
Homestead Associates in Research	Homestead	Florida	33033	Recruiting
UF Health Jacksonville Respiratory Therapy (PFT and DLCO)	Jacksonville	Florida	32209	Recruiting
Y & L Advance Health Care, Inc D/B/A Elite Clinical Research - Neurology	Miami	Florida	33144	Recruiting
Quantix Research	Miami	Florida	33173	Recruiting
Hawaii Pacific Neuroscience	Honolulu	Hawaii	96817	Recruiting
HSHS Medical Group - St. Elizabeth's Hospital	O'Fallon	Illinois	62269	Recruiting
Las Vegas Neurology Center	Las Vegas	Nevada	89106	Recruiting
Clinical Trials of South Carolina - Neurology	Charleston	South Carolina	29406	Recruiting
Ut Erlanger Neurology	Chattanooga	Tennessee	37403	Recruiting
Nerve and Muscle Center of Texas - Neurology	Houston	Texas	77030	Recruiting
Texas Institute for Neurological Disorders	Sherman	Texas	75093	Recruiting
Neurology Care Clinic	Waxahachie	Texas	75165	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07501702, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 3, 2026 · Synced Sep 8, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07501702 live on ClinicalTrials.gov.

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