An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease
Public ClinicalTrials.gov record NCT07503886. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 12-Week, Phase 2, Multicenter, Randomized, Double-Masked, Vehicle Controlled, Parallel Group Study With 2 Weeks of Follow-Up to Evaluate the Efficacy and Safety of DFL24498 0.08% Topical Ophthalmic Solution Versus Vehicle in Participants With Dry Eye Disease
Study identification
- NCT ID
- NCT07503886
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Dompé Farmaceutici S.p.A
- Industry
- Enrollment
- 417 participants
Conditions and interventions
Conditions
Interventions
- DFL24498 Drug
- Vehicle Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2026
- Primary completion
- Jan 23, 2027
- Completion
- Feb 6, 2027
- Last update posted
- Jun 25, 2026
2026 – 2027
United States locations
- U.S. sites
- 24
- U.S. states
- 14
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Center | Chandler | Arizona | 85224 | Recruiting |
| Canyon City Eyecare | Azusa | California | 91702 | Recruiting |
| Global Research Management, Inc. | Glendale | California | 91204 | Recruiting |
| United Medical Research Institute | Inglewood | California | 90301 | Recruiting |
| LoBue Laser and Eye Medical Center | Murrieta | California | 82562 | Not yet recruiting |
| Eye Research Foundation | Newport Beach | California | 92663 | Recruiting |
| NVision Clinical Research, LLC | Torrance | California | 90505 | Recruiting |
| Shettle Eye Research, Inc. | Largo | Florida | 33773 | Not yet recruiting |
| University of South Florida - Marshall Student Center | Tampa | Florida | 33612 | Not yet recruiting |
| Clayton Eye Clinical Research | Morrow | Georgia | 30260 | Recruiting |
| Price Vision Group / Cornea Research Foundation of America | Indianapolis | Indiana | 46260 | Recruiting |
| Minnesota Eye Consultants | Minnetonka | Minnesota | 55305 | Not yet recruiting |
| Tekwani Vision Center | St Louis | Missouri | 63128 | Not yet recruiting |
| Comprehensive Eye Care, Ltd. | Washington | Missouri | 63090 | Not yet recruiting |
| Asheville Eye Associates - Regional Medical Park | Asheville | North Carolina | 28803 | Not yet recruiting |
| Oculus Research, Inc. | Garner | North Carolina | 27529 | Recruiting |
| Core, Inc. | Shelby | North Carolina | 28150 | Not yet recruiting |
| Cincinnati Eye Institute | Mason | Ohio | 45040 | Not yet recruiting |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | Recruiting |
| Total Eye Care, PA - Memphis | Memphis | Tennessee | 38119 | Recruiting |
| Houston Eye Associates | Houston | Texas | 77025 | Not yet recruiting |
| Lake Travis Eye and Laser Center | Lakeway | Texas | 78738 | Recruiting |
| Alpine Research Organization, Inc. | Clinton | Utah | 84015 | Not yet recruiting |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07503886, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 25, 2026 · Synced Jul 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07503886 live on ClinicalTrials.gov.