An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

ClinicalTrials.gov ID: NCT07517263

Public ClinicalTrials.gov record NCT07517263. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 6, 2026, 8:55 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single Arm, Multicenter, Open-label Extension (OLE) Trial to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) in Participants Who Completed the Parent Lp(a)HORIZON Trial

Study identification

NCT ID: NCT07517263
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Novartis Pharmaceuticals; Industry
Enrollment: 5,700 participants

Conditions and interventions

Conditions

Not listed

Interventions

Not listed

Eligibility (public fields only)

Age range: 18 Years to 100 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 10, 2026
Primary completion: Jan 8, 2030
Completion: Jan 8, 2030
Last update posted: May 4, 2026

2026 – 2030

United States locations

U.S. sites: 76
U.S. states: 28
U.S. cities: 69

Facility	City	State	ZIP	Site status
SEC Clinical Research LLC	Andalusia	Alabama	36420	Recruiting
Heart Center Research Llc	Huntsville	Alabama	35801	Recruiting
Mobile Heart Specialists	Mobile	Alabama	36608	Recruiting
Mercy Gilbert Medical Center	Gilbert	Arizona	85297	Recruiting
Clinical Research Inst of Arizona	Sun City West	Arizona	85375	Recruiting
Eclipse Clinical Research	Tucson	Arizona	85745	Recruiting
Cardiovascular Res Found	Beverly Hills	California	90210	Recruiting
National Heart Institute	Beverly Hills	California	90211	Recruiting
UCSF	San Francisco	California	94115	Recruiting
Helping Hands Medical Associates INC	Santa Ana	California	92704	Recruiting
Manshadi Heart Institute	Stockton	California	95204	Recruiting
Interv Cardiology Med Grp	West Hills	California	91307	Recruiting
Chase Medical Research LLC	Waterbury	Connecticut	06708	Recruiting
Bay Area Cardiology Assoc	Brandon	Florida	33511	Recruiting
Jacksonville Center for Clinical Research	Jacksonville	Florida	32216	Recruiting
Advanced Research for Health Improvement LLC	Naples	Florida	34102	Recruiting
Peace River Cardiovascular Center	Port Charlotte	Florida	33952	Recruiting
Progressive Medical Research	Port Orange	Florida	32127	Recruiting
East Coast Inst for Research LLC	Saint Augustine	Florida	32086	Recruiting
Cardiology Partners Clinical Research Institute	Wellington	Florida	33449	Recruiting
Emory University	Atlanta	Georgia	30322	Recruiting
Cardiovascular Consultants of S GA	Thomasville	Georgia	31792	Recruiting
Krannert Institute of Cardiology	Indianapolis	Indiana	46202 4800	Recruiting
University of Kansas Hospital	Kansas City	Kansas	66160	Recruiting
Cotton O Neil Clinical Res Center	Topeka	Kansas	66606	Recruiting
Cardiovascular Associates Research	Covington	Louisiana	70433	Recruiting
Louisiana Heart Center Research	Covington	Louisiana	70433	Recruiting
Horizon Research Grp	Lafayette	Louisiana	70501	Recruiting
Omega Clinical Research	Metairie	Louisiana	70006	Recruiting
CV Ins of the South	Opelousas	Louisiana	70570	Recruiting
Grace Research Llc	Shreveport	Louisiana	71105	Recruiting
Southern Clinical Research	Zachary	Louisiana	70791	Recruiting
Sinai Ct for Throm Res and Drug Dev	Baltimore	Maryland	21209	Recruiting
Anderson Medical Research	Ft. Washington	Maryland	20744	Recruiting
Adventist HealthCare Shady Grove Medical Center	Rockville	Maryland	20850	Recruiting
MGH	Boston	Massachusetts	02114 2696	Recruiting
Wayne State University	Detroit	Michigan	48201	Recruiting
AA Medical Research Center	Flint	Michigan	48504	Recruiting
Western Michigan University	Kalamazoo	Michigan	49008	Recruiting
Metro Health Univ of MI Health	Wyoming	Michigan	49519	Recruiting
Saint Johns Hospital	Maplewood	Minnesota	55109	Recruiting
University Of Minnesota	Minneapolis	Minnesota	55455	Recruiting
Stern Cardiovascular Foundation Inc	Southaven	Mississippi	38671	Recruiting
StudyMetrix Research	City of Saint Peters	Missouri	63303	Recruiting
Quality Clinical Research	Omaha	Nebraska	68114	Recruiting
Overlook Medical Center	Summit	New Jersey	07901	Recruiting
Northwell Health	Manhasset	New York	11030	Recruiting
Weill Cornell Medical Center	New York	New York	10021	Recruiting
Lenox Hill Hospital	New York	New York	43210	Recruiting
Northwell Health Physician Peconic	Riverhead	New York	11901	Recruiting
Novant Health Heart Vas Inst	Charlotte	North Carolina	28204	Recruiting
Medication Management LLC	Greensboro	North Carolina	27405	Recruiting
Accellacare US Inc	Raleigh	North Carolina	27609	Recruiting
Wake Forest University Baptist Medical Center	Winston-Salem	North Carolina	27157	Recruiting
Aultman Hospital	Canton	Ohio	44710	Recruiting
Lindner Ctr At The Christ Hosp	Cincinnati	Ohio	45219	Recruiting
Rama Research LLC	Marion	Ohio	43302	Recruiting
Lancaster General Health	Lancaster	Pennsylvania	17603	Recruiting
Cardiology Consultants of Philadelphia	Yardley	Pennsylvania	19067	Recruiting
Monument Health Clinical Research	Rapid City	South Dakota	57701	Recruiting
The Stern Cardiovascular Foundation	Germantown	Tennessee	38138	Recruiting
Cardiovascular Res of Knoxville LLC	Powell	Tennessee	37849	Recruiting
Soltero Cardiovascular Research Center	Dallas	Texas	75226	Recruiting
North Texas Endocrine Center	Dallas	Texas	75231	Recruiting
SW Family Medicine Associates	Dallas	Texas	75235	Recruiting
Grace Research	Marshall	Texas	75670	Recruiting
Northwest Houston Clinical Research PLLC	Tomball	Texas	77375	Recruiting
Progressive Clinical Research	Bountiful	Utah	84010	Recruiting
The University of Utah	Salt Lake City	Utah	84132-0001	Recruiting
Inova Fairfax Hospital	Falls Church	Virginia	22042	Recruiting
Virginia Heart	Falls Church	Virginia	22042	Recruiting
Carient Heart and Vascular	Manassas	Virginia	20109	Recruiting
Dominion Medical Associates	Richmond	Virginia	23219	Recruiting
Harborview Medical Center	Seattle	Washington	98104	Recruiting
Swedish Medical Center-Cardiovascular Research	Seattle	Washington	98122	Recruiting
West Virginia University Hospital	Morgantown	West Virginia	26506	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 235 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07517263, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 4, 2026 · Synced May 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07517263 live on ClinicalTrials.gov.

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