ClinicalTrials.gov record
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
ClinicalTrials.gov ID: NCT07517263
Public ClinicalTrials.gov record NCT07517263. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single Arm, Multicenter, Open-label Extension (OLE) Trial to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) in Participants Who Completed the Parent Lp(a)HORIZON Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This open-label extension study provides post-trial access to pelacarsen (TQJ230) to participants who have successfully completed the double-blind parent study (CTQJ230A12301). Study has been terminated by sponsor following the outcome of the Lp(a)HORIZON study (NCT04023552), which did not meet its primary endpoint.
Study identification
- NCT ID
- NCT07517263
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 5,700 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2026 (Actual)
- Primary completion
- Jan 9, 2030 (Estimated)
- Completion
- Jan 9, 2030 (Estimated)
- Last update posted
- Oct 14, 2026
2026 – 2030
United States locations
- U.S. sites
- 120
- U.S. states
- 35
- U.S. cities
- 104
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| SEC Clinical Research LLC | Andalusia | Alabama | 36420 | — |
| Heart Center Research Llc | Huntsville | Alabama | 35801 | — |
| Mobile Heart Specialists | Mobile | Alabama | 36608 | — |
| Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Clinical Research Inst of Arizona | Sun City West | Arizona | 85375 | — |
| Eclipse Clinical Research | Tucson | Arizona | 85745 | — |
| Cardiology and Medicine Clinic PA | Little Rock | Arkansas | 72204 | — |
| Cardiovascular Res Found | Beverly Hills | California | 90210 | — |
| National Heart Institute | Beverly Hills | California | 90211 | — |
| Valley Clinical Trials Inc | Covina | California | 91723 | — |
| Diabetes Lipid Management Center | Huntington Beach | California | 92648 | — |
| University of Calif Irvine Med Cntr | Irvine | California | 92660 | — |
| Memorial Care Health System | Long Beach | California | 90806 | — |
| Keck Medical Center USC | Los Angeles | California | 90033 | — |
| Valley Clinical Trials | Northridge | California | 91325 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| UCSF | San Francisco | California | 94115 | — |
| Manshadi Heart Institute | Stockton | California | 95204 | — |
| Interv Cardiology Med Grp | West Hills | California | 91307 | — |
| Univ Of Color Anschutz Med Center | Aurora | Colorado | 80045 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | — |
| Bay Area Cardiology Assoc | Brandon | Florida | 33511 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Advanced Research for Health Improvement LLC | Naples | Florida | 34102 | — |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| East Coast Inst for Research LLC | Saint Augustine | Florida | 32086 | — |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | — |
| Piedmont Heart Institute | Atlanta | Georgia | 30309 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Cardiovascular Consultants of S GA | Thomasville | Georgia | 31792 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Advocate Lutheran General Childrens Hospital | Park Ridge | Illinois | 60068 | — |
| Krannert Institute of Cardiology | Indianapolis | Indiana | 46202-4800 | — |
| Uni Of Iowa Hospitals And Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Cotton O Neil Clinical Res Center | Topeka | Kansas | 66606 | — |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| Louisiana Heart Center Research | Covington | Louisiana | 70433 | — |
| CV Institute of the South | Houma | Louisiana | 70360 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| Tulane Center for Clinical Research | New Orleans | Louisiana | 70112 | — |
| CV Ins of the South | Opelousas | Louisiana | 70570 | — |
| Grace Research Llc | Shreveport | Louisiana | 71105 | — |
| Louisiana Heart Center Research | Slidell | Louisiana | 70458 | — |
| Southern Clinical Research | Zachary | Louisiana | 70791 | — |
| Maine Health Cardiology | Scarborough | Maine | 04074 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Sinai Ct for Throm Res and Drug Dev | Baltimore | Maryland | 21209 | — |
| Johns Hopkins Univ School of Med | Baltimore | Maryland | 21287 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Adventist HealthCare Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| MGH | Boston | Massachusetts | 02114-2696 | — |
| Brigham and Womens Hosp Harvard Med School | Boston | Massachusetts | 02115 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| Western Michigan University | Kalamazoo | Michigan | 49008 | — |
| McLaren Ctr Research Innovation | Petoskey | Michigan | 49770 | — |
| Central Michigan University | Saginaw | Michigan | 48601 | — |
| Metro Health Univ of MI Health | Wyoming | Michigan | 49519 | — |
| Saint Johns Hospital | Maplewood | Minnesota | 55109 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| University Of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Belzoni Clinical Research | Belzoni | Mississippi | 39038 | — |
| Stern Cardiovascular Foundation Inc | Southaven | Mississippi | 38671 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Washington Univ School Of Medicine | St Louis | Missouri | 63110 | — |
| Mercy Hospital St Louis | St Louis | Missouri | 63141 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| The Valley Hospital | Ridgewood | New Jersey | 07450 | — |
| Overlook Medical Center | Summit | New Jersey | 07901 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| Weill Cornell Medical Center | New York | New York | 10021 | — |
| Icahn School of Med at Mt Sinai | New York | New York | 10029 | — |
| Lenox Hill Hospital | New York | New York | 43210 | — |
| Northwell Health Physician Peconic | Riverhead | New York | 11901 | — |
| Novant Health Heart Vas Inst | Charlotte | North Carolina | 28204 | — |
| Medication Management LLC | Greensboro | North Carolina | 27405 | — |
| Accellacare US Inc | Raleigh | North Carolina | 27609 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Akron Hospital Summa Health System | Akron | Ohio | 44309 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Lindner Ctr At The Christ Hosp | Cincinnati | Ohio | 45219 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Rama Research LLC | Marion | Ohio | 43302 | — |
| Lancaster General Health | Lancaster | Pennsylvania | 17603 | — |
| Perelman School of Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Cardiology Consultants of Philadelphia | Yardley | Pennsylvania | 19067 | — |
| Monument Health Clinical Research | Rapid City | South Dakota | 57701 | — |
| The Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | — |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | — |
| Vanderbilt Univ Medi Cen | Nashville | Tennessee | 37232 | — |
| Cardiovascular Res of Knoxville LLC | Powell | Tennessee | 37849 | — |
| Soltero Cardiovascular Research Center | Dallas | Texas | 75226 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| SW Family Medicine Associates | Dallas | Texas | 75235 | — |
| Baylor College Of Medicine | Houston | Texas | 77030 | — |
| Grace Research | Marshall | Texas | 75670 | — |
| Northwest Houston Clinical Research PLLC | Tomball | Texas | 77375 | — |
| Progressive Clinical Research | Bountiful | Utah | 84010 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| The University of Utah | Salt Lake City | Utah | 84132-0001 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Carient Heart and Vascular | Manassas | Virginia | 20109 | — |
| Dominion Medical Associates | Richmond | Virginia | 23219 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| Swedish Medical Center-Cardiovascular Research | Seattle | Washington | 98122 | — |
| Univ of Washington Medical Center | Seattle | Washington | 98195 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
| St Luke s Medical Center Aurora | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 526 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07517263, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07517263 live on ClinicalTrials.gov.