ClinicalTrials.gov record
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
ClinicalTrials.gov ID: NCT07522073
Public ClinicalTrials.gov record NCT07522073. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Phase 3 Study of Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma (DAWN-303)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of standard chemotherapy with or without INCB161734 in participants with metastatic pancreatic ductal adenocarcinoma (PDAC).
Study identification
- NCT ID
- NCT07522073
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 588 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 8, 2026
- Primary completion
- Sep 14, 2028
- Completion
- Mar 18, 2029
- Last update posted
- Aug 5, 2026
2026 – 2029
United States locations
- U.S. sites
- 70
- U.S. states
- 30
- U.S. cities
- 59
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigative Site US058 | Birmingham | Alabama | 35233 | Not yet recruiting |
| Investigative Site US016 | Anchorage | Alaska | 99508 | Recruiting |
| Investigative Site US026 | Chandler | Arizona | 85224 | Not yet recruiting |
| Investigative Site US045 | Tucson | Arizona | 85719 | Not yet recruiting |
| Investigative Site US051 | Duarte | California | 91010 | Not yet recruiting |
| Investigative Site US085 | Fullerton | California | 92835 | Not yet recruiting |
| Investigative Site US054 | La Jolla | California | 92093 | Not yet recruiting |
| Investigative Site US086 | Long Beach | California | 90806-1650 | Not yet recruiting |
| Investigative Site US027 | Los Angeles | California | 90027 | Recruiting |
| Investigative Site US036 | Los Angeles | California | 90089 | Recruiting |
| Investigative Site US048 | Los Angeles | California | 91204-3640 | Recruiting |
| Investigative Site US049 | Orange | California | 92868 | Not yet recruiting |
| Investigative Site US034 | San Francisco | California | 94143 | Not yet recruiting |
| Investigative Site US001 | Santa Monica | California | 90404 | Not yet recruiting |
| Investigative Site US071 | Denver | Colorado | 80218 | Recruiting |
| Investigative Site US013 | Washington D.C. | District of Columbia | 20007 | Not yet recruiting |
| Investigative Site US046 | Washington D.C. | District of Columbia | 20016 | Not yet recruiting |
| Investigative Site US072 | Fort Myers | Florida | 33901 | Recruiting |
| Investigative Site US083 | Jacksonville | Florida | 32207 | Not yet recruiting |
| Investigative Site US075 | Miami | Florida | 33136 | Not yet recruiting |
| Investigative Site US074 | St. Petersburg | Florida | 33701-4553 | Recruiting |
| Investigative Site US073 | West Palm Beach | Florida | 33401 | Recruiting |
| Investigative Site US023 | Atlanta | Georgia | 30322 | Not yet recruiting |
| Investigative Site US079 | Chicago | Illinois | 60637 | Not yet recruiting |
| Investigative Site US030 | Evanston | Illinois | 60201 | Not yet recruiting |
| Investigative Site US005 | Naperville | Illinois | 60540 | Recruiting |
| Investigative Site US009 | Springfield | Illinois | 62702 | Recruiting |
| Investigative Site US021 | Indianapolis | Indiana | 46250 | Not yet recruiting |
| Investigative Site US007 | New Orleans | Louisiana | 70121 | Not yet recruiting |
| Investigative Site US022 | Boston | Massachusetts | 02215 | Recruiting |
| Investigative Site US006 | Ann Arbor | Michigan | 48109 | Not yet recruiting |
| Investigative Site US010 | Detroit | Michigan | 48201 | Not yet recruiting |
| Investigative Site US078 | Grand Rapids | Michigan | 49503 | Recruiting |
| Investigative Site US012 | Ypsilanti | Michigan | 48197 | Not yet recruiting |
| Investigative Site US066 | Maple Grove | Minnesota | 55369 | Recruiting |
| Investigative Site US047 | Hattiesburg | Mississippi | 39401 | Not yet recruiting |
| Investigative Site US084 | Reno | Nevada | 89502 | Not yet recruiting |
| Investigative Site US077 | Hackensack | New Jersey | 07601 | Recruiting |
| Investigative Site US017 | Morristown | New Jersey | 07960 | Recruiting |
| Investigative Site US059 | Lake Success | New York | 11042 | Recruiting |
| Investigative Site US031 | New York | New York | 10016 | Not yet recruiting |
| Investigative Site US041 | New York | New York | 10029 | Not yet recruiting |
| Investigative Site US003 | New York | New York | 10065 | Recruiting |
| Investigative Site US029 | The Bronx | New York | 10461 | Recruiting |
| Investigative Site US035 | Chapel Hill | North Carolina | 27514 | Not yet recruiting |
| Investigative Site US050 | Cleveland | Ohio | 44106 | Not yet recruiting |
| Investigative Site US020 | Cleveland | Ohio | 44195 | Recruiting |
| Investigative Site US033 | Columbus | Ohio | 43210 | Not yet recruiting |
| Investigative Site US042 | Portland | Oregon | 97239 | Not yet recruiting |
| Investigative Site US008 | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Investigative Site US043 | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Investigative Site US056 | Pittsburgh | Pennsylvania | 15212 | Not yet recruiting |
| Investigative Site US082 | Charleston | South Carolina | 29425 | Not yet recruiting |
| Investigative Site US055 | Sioux Falls | South Dakota | 57105-2140 | Recruiting |
| Investigative Site US039 | Nashville | Tennessee | 37203 | Not yet recruiting |
| Investigative Site US060 | Nashville | Tennessee | 37203 | Recruiting |
| Investigative Site US070 | Nashville | Tennessee | 37232-6309 | Not yet recruiting |
| Investigative Site US067 | Dallas | Texas | 75246 | Recruiting |
| Investigative Site US062 | Denison | Texas | 75020 | Recruiting |
| Investigative Site US011 | Houston | Texas | 77030 | Recruiting |
| Investigative Site US080 | San Antonio | Texas | 78229 | Not yet recruiting |
| Investigative Site US063 | San Antonio | Texas | 78240 | Recruiting |
| Investigative Site US053 | Salt Lake City | Utah | 84112 | Not yet recruiting |
| Investigative Site US076 | Charlottesville | Virginia | 22903 | Not yet recruiting |
| Investigative Site US057 | Fairfax | Virginia | 22031 | Not yet recruiting |
| Investigative Site US065 | Fairfax | Virginia | 22031 | Recruiting |
| Investigative Site US064 | Salem | Virginia | 24153 | Recruiting |
| Investigative Site US081 | Olympia | Washington | 98506 | Recruiting |
| Investigative Site US032 | Seattle | Washington | 98122 | Not yet recruiting |
| Investigative Site US044 | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 149 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07522073, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2026 · Synced Sep 1, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07522073 live on ClinicalTrials.gov.