EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety

ClinicalTrials.gov ID: NCT07523581

Public ClinicalTrials.gov record NCT07523581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 21, 2026, 4:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Delayed-Start Study to Evaluate the Efficacy and Safety of Exaluren in Alport Syndrome Patients With Nonsense Mutations in COL4A3/4/5 Genes

Study identification

NCT ID: NCT07523581
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Eloxx Pharmaceuticals, Inc.; Industry
Enrollment: 24 participants

Conditions and interventions

Conditions

Interventions

Exaluren Drug

Drug

Eligibility (public fields only)

Age range: 12 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 29, 2026
Primary completion: Jun 29, 2027
Completion: Dec 30, 2027
Last update posted: Jul 14, 2026

2026 – 2027

United States locations

U.S. sites: 8
U.S. states: 7
U.S. cities: 8

Facility	City	State	ZIP	Site status
University of California, Los Angeles	Los Angeles	California	90095	Not yet recruiting
Stanford University	Stanford	California	94305	Not yet recruiting
Denver Nephrologists PC, Colorado Kidney Care PC	Denver	Colorado	80220	Recruiting
University of Minnesota	Minneapolis	Minnesota	55455	Not yet recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Not yet recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Not yet recruiting
University of Pennsylvania	Philadelphia	Pennsylvania	19104	Not yet recruiting
Renal Associates, P.A.	San Antonio	Texas	78109	Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07523581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 14, 2026 · Synced Jul 21, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07523581 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →