A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants
Public ClinicalTrials.gov record NCT07535034. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Dotinurad in Adult Participants With Gout Who Are Intolerant to Xanthine Oxidase Inhibitors or Failed Uricase Treatment
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this trial is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 in participants with gout who are XOI intolerant or have failed uricase treatment.
Study identification
- NCT ID
- NCT07535034
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 90 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 8, 2026 (Actual)
- Primary completion
- Jul 2027 (Estimated)
- Completion
- Aug 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2026 – 2027
United States locations
- U.S. sites
- 41
- U.S. states
- 17
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Kirklin Clinic of UAB Hospital | Birmingham | Alabama | 35233 | Recruiting |
| Arizona Arthritis & Rheumatology Research, PLLC | Phoenix | Arizona | 85032 | Recruiting |
| AARA Clinical Research-SE Tucson | Tucson | Arizona | 85748 | Recruiting |
| Amicis Research Center | Granada Hills | California | 91344 | Recruiting |
| Cohen Medical Center | Thousand Oaks | California | 91360 | Recruiting |
| Solace Clinical Research | Tustin | California | 92780 | Recruiting |
| Denver Arthritis Clinic - Lowry | Denver | Colorado | 80230 | Recruiting |
| Omega Research Group | DeBary | Florida | 32713 | Recruiting |
| Herco Medical and Research Center, Inc | Flagami | Florida | 33126 | Recruiting |
| New Generation of Medical Research | Hialeah | Florida | 33016 | Recruiting |
| Health Awareness, Inc. | Jupiter | Florida | 33458 | Recruiting |
| Clinical Research of Central Florida | Lakeland | Florida | 33805 | Recruiting |
| D&H Pompano Research Center, LLC | Margate | Florida | 33063 | Recruiting |
| Panax Clinical Research | Miami | Florida | 33014 | Recruiting |
| Anchor Medical Research | Miami | Florida | 33176 | Recruiting |
| Southwest Atlanta Internal Medicine | Atlanta | Georgia | 30331 | Recruiting |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | Recruiting |
| Research Group of Lexington, LLC | Lexington | Kentucky | 40503 | Recruiting |
| MD Medical Research | Oxon Hill | Maryland | 20745 | Recruiting |
| AARA Clinical Research-Arthritis and Rheumatism Associates | Rockville | Maryland | 20850 | Recruiting |
| Clinical Research Institute of Michigan | Saint Clair Shores | Michigan | 48081 | Recruiting |
| Revival Research Institute | Sterling Heights | Michigan | 48313 | Recruiting |
| Oakland Medical Research Center | Troy | Michigan | 48085 | Recruiting |
| Velocity Clinical Research | Norfolk | Nebraska | 68701 | Recruiting |
| Las Vegas Clinical Trials | Las Vegas | Nevada | 89030 | Recruiting |
| Premier Health Research | Sparta | New Jersey | 07871 | Recruiting |
| Ellipsis Research Group | Brooklyn | New York | 11215 | Recruiting |
| Drug Trials America | Hartsdale | New York | 10530 | Recruiting |
| DJL Clinical Research | Charlotte | North Carolina | 28211 | Recruiting |
| Shelby Clinical Research | Shelby | North Carolina | 28150 | Recruiting |
| Hometown Urgent Care and Research | Dayton | Ohio | 45424 | Recruiting |
| Amarillo Premier Research | Amarillo | Texas | 79124 | Recruiting |
| Zenos Clinical Research | Dallas | Texas | 75230 | Recruiting |
| Epic Medical Research | DeSoto | Texas | 75115 | Recruiting |
| Pioneer Research Solutions | Houston | Texas | 77479 | Recruiting |
| R&H Clinical Research - Westborough Drive | Katy | Texas | 77449 | Recruiting |
| Southwest Rheumatology Research | Mesquite | Texas | 75150 | Recruiting |
| Discovery Clinical Trials, LLC | San Antonio | Texas | 78229 | Recruiting |
| DM Clinical Research | Tomball | Texas | 77375 | Recruiting |
| Velocity Clinical Research (Impact Research Institute) | Waco | Texas | 76710 | Recruiting |
| Digestive Health Research of North Texas | Wichita Falls | Texas | 76301 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07535034, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07535034 live on ClinicalTrials.gov.