Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

ClinicalTrials.gov ID: NCT07575399

Public ClinicalTrials.gov record NCT07575399. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 24, 2026, 2:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-label Trial to Evaluate the Efficacy, Safety and Tolerability of Switching From the Glucagon-like Peptide-1 Receptor Agonists to Maridebart Cafraglutide in Adult Participants With Obesity or Overweight

Study identification

NCT ID: NCT07575399
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Amgen; Industry
Enrollment: 300 participants

Conditions and interventions

Conditions

Obesity or Overweight

Interventions

Maridebart Cafraglutide Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 10, 2026
Primary completion: Jan 2, 2028
Completion: Feb 27, 2028
Last update posted: Jul 22, 2026

2026 – 2028

United States locations

U.S. sites: 43
U.S. states: 17
U.S. cities: 40

Facility	City	State	ZIP	Site status
Cahaba Research, Inc.	Pelham	Alabama	35124	Recruiting
Arizona Clinical Trials	Chandler	Arizona	85224	Recruiting
Epic Medical Research - Sun City	Sun City	Arizona	85351	Recruiting
Desert Oasis Healthcare Medical Group	Palm Springs	California	92262	Recruiting
Inland Empire Liver Foundation	Rialto	California	92377	Recruiting
Peninsula Research Associates	Rolling Hills Estates	California	90274	Recruiting
Apex Clinical Research	San Diego	California	92120	Recruiting
Southern California Clinical Research	Santa Ana	California	92701	Recruiting
University of Florida Department of Medicine	Gainesville	Florida	32610	Recruiting
Aga Clinical Trials	Hialeah	Florida	33012	Recruiting
South Florida Clinical Research	Margate	Florida	33063	Recruiting
New Horizon Research Center	Miami	Florida	33165	Recruiting
Research Institute of South Florida	Miami	Florida	33173	Recruiting
Clinical Neuroscience Solutions	Orlando	Florida	32801	Recruiting
Florida Institute for Clinical Research	Orlando	Florida	32825	Recruiting
Progressive Medical Research	Port Orange	Florida	32127	Recruiting
Charter Research - The Villages	The Villages	Florida	32162	Recruiting
Nsc Research	Johns Creek	Georgia	30024	Recruiting
Rophe Adult and Pediatric Medicine/Sky Clinical Research Network Group	Union City	Georgia	30291	Recruiting
North Georgia Clinical Research	Woodstock	Georgia	30189	Recruiting
Solaris Clinical Research	Meridian	Idaho	83646	Recruiting
Endeavor Health	Skokie	Illinois	60077	Recruiting
Pennington Biomedical Research Center	Baton Rouge	Louisiana	70808	Recruiting
Arcturus Healthcare, Public Limited Company, Troy Internal Medicine Research Division	Troy	Michigan	48098	Recruiting
Sky Integrative Medical Center	Ridgeland	Mississippi	39157	Recruiting
Excel Clinical Research	Las Vegas	Nevada	89109	Recruiting
Icahn School of Medicine at Mount Sinai	New York	New York	10029	Recruiting
Rochester Clinical Research	Rochester	New York	14609	Recruiting
Centricity Research Morehead City Specialty	Morehead City	North Carolina	28557	Recruiting
Accellacare of Raleigh	Raleigh	North Carolina	27609	Recruiting
Accellacare Research of Wilmington	Wilmington	North Carolina	28401	Recruiting
Epic Medical Research - Oklahoma	Chickasha	Oklahoma	73018	Recruiting
Lynn Health Science Institute	Oklahoma City	Oklahoma	73112	Recruiting
Altoona Center for Clinical Research	Duncansville	Pennsylvania	16635	Recruiting
Epic Medical Research - DeSoto	DeSoto	Texas	75115	Recruiting
South Texas Research Institute	Edinburg	Texas	78539	Recruiting
Biopharma Informatic, LLC	Houston	Texas	77043	Recruiting
Research Physicians Network, LLC	Houston	Texas	77089	Recruiting
Texas Institute of Cardiology	McKinney	Texas	75071	Recruiting
North Hills Medical Research	North Richland Hills	Texas	76180	Recruiting
VIP Trials	San Antonio	Texas	78230	Recruiting
Northwest Houston Heart Center	Tomball	Texas	77375	Recruiting
Eastside Research Associates Health Research	Redmond	Washington	98052	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07575399, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 22, 2026 · Synced Jul 24, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07575399 live on ClinicalTrials.gov.

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