A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

ClinicalTrials.gov ID: NCT07577843

Public ClinicalTrials.gov record NCT07577843. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:48 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-blind, and Active-controlled Multicenter Study to Evaluate the Efficacy and Safety of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active Crohn's disease (a long-term, progressive \[worsens with time\] and life-threatening disease of the intestine).

Study identification

NCT ID: NCT07577843
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Janssen Research & Development, LLC; Industry
Enrollment: 460 participants

Conditions and interventions

Conditions

Crohn Disease

Interventions

JNJ-78934804 Drug
Guselkumab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 22, 2026 (Actual)
Primary completion: Jun 12, 2028 (Estimated)
Completion: Jul 12, 2030 (Estimated)
Last update posted: Oct 14, 2026

2026 – 2030

United States locations

U.S. sites: 22
U.S. states: 16
U.S. cities: 22

Facility	City	State	ZIP	Site status
Clinnova Research	Anaheim	California	92805	Recruiting
Gastro SB Clinic	Chula Vista	California	91910	Recruiting
United Medical Doctors	Los Alamitos	California	90720	Recruiting
Medical Associates Research Group, Inc.	San Diego	California	92123	Recruiting
Peak Gastroenterology Associates	Colorado Springs	Colorado	80907	Recruiting
Florida Research Center Inc.	Lakewood Rch	Florida	34211	Recruiting
Sanchez Clinical Research, Inc	Miami	Florida	33157-6575	Recruiting
GCP Clinical Research	Tampa	Florida	33609	Recruiting
Atlanta Gastroenterology Specialists	Suwanee	Georgia	30024	Recruiting
Tri-State Gastroenterology Assoc	Crestview Hills	Kentucky	41017	Recruiting
Gastroenterology Clinic of Acadiana	Lafayette	Louisiana	70503	Recruiting
GIA Metairie	Metairie	Louisiana	70006	Recruiting
Michigan Center of Medical Research	Farmington Hills	Michigan	48334	Recruiting
GIA Kansas City	Lee's Summit	Missouri	64086	Recruiting
New York Gastroenterology Associates	New York	New York	10075	Recruiting
University of North Carolina Hospital	Chapel Hill	North Carolina	27599-7080	Recruiting
Great Lakes Gastroenterology Research, LLC	Mentor	Ohio	44060	Recruiting
Digestive Disease Specialists Inc	Oklahoma City	Oklahoma	73114	Recruiting
The Oregon Clinic	Portland	Oregon	97220	Recruiting
Gastro One	Cordova	Tennessee	38018	Recruiting
Tyler Research Institute, LLC	Tyler	Texas	75701	Recruiting
GI Alliance Tacoma	Tacoma	Washington	98405	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 230 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07577843, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 14, 2026 · Synced Oct 20, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07577843 live on ClinicalTrials.gov.

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