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Not yet recruiting Phase 2 Interventional

Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

ClinicalTrials.gov ID: NCT07582159

Public ClinicalTrials.gov record NCT07582159. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 17, 2026, 8:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of Acalabrutinib, Venetoclax and Tafasitamab (AVT) in Patients With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Study identification

NCT ID
NCT07582159
Recruitment status
Not yet recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
City of Hope Medical Center
Other
Enrollment
35 participants

Conditions and interventions

Interventions

  • Acalabrutinib Drug
  • Biospecimen Collection Procedure
  • Bone Marrow Biopsy Procedure
  • Computed Tomography Procedure
  • Positron Emission Tomography Procedure
  • Tafasitamab Biological
  • Venetoclax Drug

Drug · Procedure · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 18, 2026
Primary completion
Apr 13, 2029
Completion
Apr 13, 2029
Last update posted
May 11, 2026

2026 – 2029

United States locations

U.S. sites
2
U.S. states
1
U.S. cities
2
Facility City State ZIP Site status
City of Hope Medical Center Duarte California 91010
City of Hope at Irvine Lennar Irvine California 92618

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07582159, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 11, 2026 · Synced May 17, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07582159 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →