A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

ClinicalTrials.gov ID: NCT07589608

Public ClinicalTrials.gov record NCT07589608. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 11, 2026, 5:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Parallel-Group, Double-Blind, Placebo-Controlled Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight and Without Type 2 Diabetes

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to examine the body weight-lowering efficacy and safety of macupatide plus eloralintide compared with placebo in participants with obesity or overweight and without type 2 diabetes. Participation will last about 64 weeks.

Study identification

NCT ID: NCT07589608
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Eli Lilly and Company; Industry
Enrollment: 400 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 14, 2026
Primary completion: Aug 31, 2027
Completion: Jan 31, 2028
Last update posted: Aug 5, 2026

2026 – 2028

United States locations

U.S. sites: 40
U.S. states: 20
U.S. cities: 40

Facility	City	State	ZIP	Site status
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa	Chandler	Arizona	85225	Recruiting
Headlands Research - Scottsdale	Scottsdale	Arizona	85260	Recruiting
The Institute for Liver Health II dba Arizona Liver Health-Tucson	Tucson	Arizona	85712	Recruiting
NorCal Medical Research, Inc	Greenbrae	California	94904	Recruiting
Velocity Clinical Research, Huntington Park	Huntington Park	California	90255	Recruiting
Peninsula Research Associates	Rolling Hills Estates	California	90274	Recruiting
Diablo Clinical Research, Inc.	Walnut Creek	California	94598	Recruiting
Stamford Therapeutics Consortium	Stamford	Connecticut	06905	Recruiting
New Horizon Research Center	Miami	Florida	33165	Recruiting
Indago Research & Health Center, Inc	Miami Lakes	Florida	33016	Recruiting
Suncoast Clinical Research, Inc.	New Port Richey	Florida	34652	Recruiting
Charter Research - Winter Park	Orlando	Florida	32803	Recruiting
Charter Research - Lady Lake	The Villages	Florida	32162	Recruiting
Medical Research Partners	Ammon	Idaho	83406	Recruiting
Great Lakes Clinical Trials - Ravenswood	Chicago	Illinois	60640	Recruiting
Cotton O'Neil Diabetes & Endocrinology	Topeka	Kansas	66606	Recruiting
Monroe Biomedical Research - Louisville	Louisville	Kentucky	40213	Recruiting
Knownwell	Needham	Massachusetts	02492	Recruiting
Lucida Clinical Trials	New Bedford	Massachusetts	02740	Recruiting
Headlands Research - Detroit	Southfield	Michigan	48034	Recruiting
Arcturus Healthcare , PLC, Troy Internal Medicine Research Division	Troy	Michigan	48098	Recruiting
StudyMetrix Research	City of Saint Peters	Missouri	63303	Recruiting
Clinvest Headlands Llc	Springfield	Missouri	65807	Recruiting
Las Vegas Medical Research	Las Vegas	Nevada	89128	Recruiting
Dent Neurologic Institute	Amherst	New York	14226	Recruiting
Rochester Clinical Research, LLC	Rochester	New York	14609	Recruiting
Medication Management	Greensboro	North Carolina	27405	Recruiting
Monroe Biomedical Research	Monroe	North Carolina	28112	Recruiting
Lucas Research, Inc	Morehead City	North Carolina	28557	Recruiting
Lucas Research, Inc.	New Bern	North Carolina	28562	Recruiting
CTI Clinical Research Center	Cincinnati	Ohio	45212	Recruiting
Tribe Clinical Research, LLC	Greenville	South Carolina	29607	Recruiting
Quality Medical Research	Nashville	Tennessee	37211	Recruiting
IMA Clinical Research Austin	Austin	Texas	78745	Recruiting
FutureSearch Trials of Dallas	Dallas	Texas	75251	Recruiting
PlanIt Research, PLLC	Houston	Texas	77079	Recruiting
Endeavor Clinical Trials	San Antonio	Texas	78240	Recruiting
Texas Valley Clinical Research	Weslaco	Texas	78596	Recruiting
Sovah Clinical Research-River District	Danville	Virginia	24541	Recruiting
Central Washington Health Services Association d/b/a Confluence Health	Wenatchee	Washington	98801	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07589608, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 5, 2026 · Synced Sep 11, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07589608 live on ClinicalTrials.gov.

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