A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Public ClinicalTrials.gov record NCT07592689. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled, 12-Week Study (Part A) With a 40-Week Open-label Extension (Part B) Evaluating the Efficacy and Safety of Oral DT120 Compared to Placebo in the Treatment of Adults With Major Depressive Disorder - Ascend
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Major Depressive Disorder - Ascend
Study identification
- NCT ID
- NCT07592689
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 165 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 74 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 9, 2026
- Primary completion
- Aug 31, 2027
- Completion
- May 31, 2028
- Last update posted
- Aug 9, 2026
2026 – 2028
United States locations
- U.S. sites
- 30
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | Recruiting |
| ATP Clinical Research Orange County | Orange | California | 92866 | Not yet recruiting |
| Kadima Neuropsychiatry Institute | San Diego | California | 92037 | Recruiting |
| UCSF Department of Neurology | San Francisco | California | 94158 | Not yet recruiting |
| Psychedelic Science Institute | Santa Monica | California | 90404 | Recruiting |
| Mountain View Clinical Research, Inc | Denver | Colorado | 80209 | Recruiting |
| Clinical Neuroscience Solutions, LLC (Jacksonville) | Jacksonville | Florida | 32256 | Not yet recruiting |
| K2 Medical Research (Maitland) | Maitland | Florida | 32751 | Not yet recruiting |
| Clinical Neuroscience Solutions, LLC (Orlando) | Orlando | Florida | 32801 | Not yet recruiting |
| Charter Research | Orlando | Florida | 32803 | Not yet recruiting |
| K2 Medical Research (Tampa) | Tampa | Florida | 33607 | Not yet recruiting |
| CenExel - Atlanta Center for Medical Research | Atlanta | Georgia | 30331 | Recruiting |
| CenExel - iResearch Atlanta | Decatur | Georgia | 30030 | Recruiting |
| CenExel - iResearch Savannah | Savannah | Georgia | 31405 | Recruiting |
| Uptown Research Institute | Chicago | Illinois | 60640 | Recruiting |
| Adams Clinical Boston | Boston | Massachusetts | 02116 | Recruiting |
| Adams Clinical Watertown | Boston | Massachusetts | 02472 | Recruiting |
| Vitalix Clinical | Worcester | Massachusetts | 01608 | Recruiting |
| Arch Clinical Trials, LLC | St Louis | Missouri | 63141 | Not yet recruiting |
| Redbird Research | Las Vegas | Nevada | 89119 | Recruiting |
| Adams Clinical Harlem | New York | New York | 10029 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44113 | Not yet recruiting |
| Adams Clinical Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Coastal Carolina Research | North Charleston | South Carolina | 29405 | Recruiting |
| Austin Clinical Trial Partners | Austin | Texas | 78737 | Recruiting |
| Cedar Clinical Research | Draper | Utah | 84020 | Recruiting |
| Inner Space Research | Orem | Utah | 84058 | Recruiting |
| Memory Clinic Inc. | Bennington | Vermont | 05201 | Not yet recruiting |
| Seattle Neuropsychiatric Treatment Center | Seattle | Washington | 98104 | Not yet recruiting |
| VA Portland Healthcare System | Vancouver | Washington | 98661 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07592689, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 9, 2026 · Synced Sep 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07592689 live on ClinicalTrials.gov.