Effects of Carbohydrates Versus Carbohydrates + Protein on Resistance Training Outcomes
Public ClinicalTrials.gov record NCT07600138. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Higher energy and carbohydrate intakes have been hypothesized to enhance resistance training adaptations, yet empirical evidence remains mixed. This study investigated whether supplemental carbohydrate-energy intake improves muscle hypertrophy, strength, and fatigue resistance in resistance-trained men. Twenty resistance-trained men completed a quasi-randomized, double-blinded, counterbalanced crossover trial. Participants consumed either a daily protein-only supplement (30 g protein, 4 g carbohydrate) or a daily protein-plus-carbohydrate supplement (30 g protein, 54 g carbohydrate) for 8 weeks each, followed by crossover, while continuing their habitual training and diet. Primary outcomes included lean mass (dual-energy x-ray absorptiometry), muscle thickness and cross-sectional area (ultrasound), back squat one-repetition maximum, knee extensor peak torque, and fatigue index. The carbohydrate-protein supplement produced significantly higher daily energy and carbohydrate intake compared to the protein-only supplement, with no differences in protein intake, fat intake, or training volume. No significant between-condition differences were observed for any outcome. These results suggest that modest increases in carbohydrate-energy intake outside of an energy deficit are unlikely to meaningfully enhance muscle hypertrophy, strength, or fatigue resistance in trained men.
Study identification
- NCT ID
- NCT07600138
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 25 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 40 Years
- Sex
- Male
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 11, 2025
- Primary completion
- Sep 14, 2025
- Completion
- Sep 15, 2025
- Last update posted
- May 19, 2026
2025
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| School of Kinesiology | Auburn | Alabama | 36879-5432 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07600138, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 19, 2026 · Synced Sep 7, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07600138 live on ClinicalTrials.gov.