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Recruiting Phase 4 Interventional

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

ClinicalTrials.gov ID: NCT07609914

Public ClinicalTrials.gov record NCT07609914. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 19, 2026, 5:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 4, SINGLE-ARM, OPEN-LABEL STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND EFFECTIVENESS OF REDOSING OF RIMEGEPANT IN PARTICIPANTS 18 YEARS OF AGE OR OLDER FOR THE ACUTE TREATMENT OF MIGRAINE

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose of the same medication within the recommended dose limit in people with headache relapse after successful initial treatment of a migraine attack. The primary purpose of this study is to evaluate the safety and tolerability of redosing of rimegepant when taken for the acute treatment of a migraine attack, as it is possible that some patients may benefit from a second dose of rimegepant in this setting.

Study identification

NCT ID
NCT07609914
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 4
Lead sponsor
Pfizer
Industry
Enrollment
400 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 27, 2026
Primary completion
May 14, 2028
Completion
May 14, 2028
Last update posted
Aug 23, 2026

2026 – 2028

United States locations

U.S. sites
12
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Hope Clinical Research Canoga Park California 91303 Recruiting
Clinical Research Institute Los Angeles California 90048 Recruiting
Neurology Offices of South Florida Boca Raton Florida 33428 Recruiting
Brainstorm Research Miami Florida 33176 Recruiting
Clinical Neuroscience Solutions Orlando Florida 32801 Recruiting
New England Regional Headache Center Worcester Massachusetts 01609 Recruiting
Michigan Headache & Neurological Institute Ann Arbor Michigan 48104 Recruiting
Proven Endpoints, LLC Ridgeland Mississippi 39157 Recruiting
Headache Wellness Center Greensboro North Carolina 27405 Recruiting
FutureSearch Trials of Neurology Austin Texas 78731 Recruiting
FutureSearch Trials of Dallas Dallas Texas 75251 Recruiting
Medstar Health - Department of Neurology McLean Virginia 22101 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07609914, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 23, 2026 · Synced Sep 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07609914 live on ClinicalTrials.gov.

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