A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia

ClinicalTrials.gov ID: NCT07610278

Public ClinicalTrials.gov record NCT07610278. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 1, 2026, 11:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Randomized, Double-blind, Factorial Design Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of HDY015 Administered as a Free Combination of QCZ484 and Inclisiran Compared to QCZ484, Inclisiran, and Placebo in Participants With Hypertension and Concomitant Hypercholesterolemia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multicenter, randomized, double-blind, factorial design Phase 2 study to evaluate the pharmacodynamics, safety and tolerability of a combination of QCZ484 and inclisiran compared to QCZ484, inclisiran, and placebo in participants with hypertension and concomitant hypercholesterolemia.

Study identification

NCT ID: NCT07610278
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Novartis Pharmaceuticals; Industry
Enrollment: 120 participants

Conditions and interventions

Conditions

Hypercholesterolaemia

Interventions

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 28, 2026
Primary completion: Apr 27, 2027
Completion: Feb 2, 2028
Last update posted: Jul 29, 2026

2026 – 2028

United States locations

U.S. sites: 27
U.S. states: 12
U.S. cities: 27

Facility	City	State	ZIP	Site status
G and L Research LLC	Foley	Alabama	36535	Recruiting
The Center for Clinical Trials	Saraland	Alabama	36571	Recruiting
Clinical Trials Research	Lincoln	California	95648	Recruiting
Downtown L A Research Center Inc	Los Angeles	California	90017	Recruiting
Valley Clinical Trials	Northridge	California	91325	Recruiting
Flourish Medical Clinical Trials	Boca Raton	Florida	33434	Recruiting
Clinical Research of Brandon LLC	Brandon	Florida	33511	Recruiting
ALL Medical Research LLC	Cooper City	Florida	33024	Recruiting
AMR Miami	Coral Gables	Florida	33134	Recruiting
Universal Axon Clinical Research	Doral	Florida	33166	Recruiting
East Coast Institute for Research	Jacksonville	Florida	32216	Recruiting
Entrust Clinical Research	Miami	Florida	33176	Recruiting
Inpatient Research Clinical LLC	Miami Lakes	Florida	33014	Recruiting
American Research Centers of FL	Pembroke Pines	Florida	33027	Recruiting
East Coast Inst for Research LLC	Saint Augustine	Florida	32086	Recruiting
East Coast Research	Canton	Georgia	30114	Recruiting
Great Lakes Clinical Trials	Chicago	Illinois	60640	Recruiting
AMR Chicago	Niles	Illinois	60714	Recruiting
Alliance for Multispecialty Research	Wichita	Kansas	67207	Recruiting
Monroe Research Llc	West Monroe	Louisiana	71291	Recruiting
Anderson Medical Research	Ft. Washington	Maryland	20744	Recruiting
Capitol Cardiology Associates	Lanham	Maryland	20706	Recruiting
Monroe Biomedical Research	Monroe	North Carolina	28112	Recruiting
Walker Family Care	Little River	South Carolina	29566	Recruiting
Synergy Group Medical LLC	Houston	Texas	77061	Recruiting
Manassas Clinical Research Center	Manassas	Virginia	20110	Recruiting
Dominion Medical Associates	Richmond	Virginia	23219	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07610278, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 29, 2026 · Synced Sep 1, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07610278 live on ClinicalTrials.gov.

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