AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Public ClinicalTrials.gov record NCT07611110. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicentre, Randomised Controlled Study to Evaluate the Efficacy and Safety of AZD2265 (FPI-2265) ²²⁵Ac-PSMA-I&T Compared With Standard of Care in Patients With PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The intention of the study is to demonstrate superiority of AZD2265 relative to standard of care treatments by assessment of radiographic progression-free survival (rPFS) and overall survival (OS) in participants with mCRPC.
Study identification
- NCT ID
- NCT07611110
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 670 participants
Conditions and interventions
Interventions
- Actinium (225Ac) zadavotide guraxetan (AZD2265 [FPI-2265]) Drug
- Cabazitaxel Drug
- Abiraterone Drug
- Enzalutamide Drug
- Apalutamide Drug
- Darolutamide Drug
- Deutenzalutamide Drug
- Radium-223 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 3, 2026
- Primary completion
- Jun 3, 2029
- Completion
- Jun 5, 2030
- Last update posted
- Aug 25, 2026
2026 – 2030
United States locations
- U.S. sites
- 26
- U.S. states
- 20
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Dothan | Alabama | 36303 | Recruiting |
| Research Site | Phoenix | Arizona | 85004 | Not yet recruiting |
| Research Site | Duarte | California | 91010 | Not yet recruiting |
| Research Site | Irvine | California | 92618 | Not yet recruiting |
| Research Site | Newport Beach | California | 92660 | Recruiting |
| Research Site | San Francisco | California | 94143 | Not yet recruiting |
| Research Site | Aurora | Colorado | 80045 | Not yet recruiting |
| Research Site | Miami | Florida | 33165 | Recruiting |
| Research Site | O'Fallon | Illinois | 62269 | Not yet recruiting |
| Research Site | Metairie | Louisiana | 70006 | Recruiting |
| Research Site | Detroit | Michigan | 48201 | Withdrawn |
| Research Site | Grand Rapids | Michigan | 49503 | Not yet recruiting |
| Research Site | St Louis | Missouri | 63104 | Not yet recruiting |
| Research Site | Omaha | Nebraska | 68130 | Recruiting |
| Research Site | Albuquerque | New Mexico | 87109 | Not yet recruiting |
| Research Site | New Hyde Park | New York | 11042 | Not yet recruiting |
| Research Site | New York | New York | 10065 | Not yet recruiting |
| Research Site | Cleveland | Ohio | 44195 | Not yet recruiting |
| Research Site | Dayton | Ohio | 45415 | Not yet recruiting |
| Research Site | Portland | Oregon | 97239 | Not yet recruiting |
| Research Site | Pittsburgh | Pennsylvania | 15232 | Not yet recruiting |
| Research Site | Myrtle Beach | South Carolina | 29572 | Not yet recruiting |
| Research Site | Nashville | Tennessee | 37203 | Not yet recruiting |
| Research Site | Houston | Texas | 77042 | Recruiting |
| Research Site | Salt Lake City | Utah | 84106 | Not yet recruiting |
| Research Site | Tacoma | Washington | 98405 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 106 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07611110, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07611110 live on ClinicalTrials.gov.