PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
Public ClinicalTrials.gov record NCT07611214. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PRESERVE: A Multi-Center Phase 4 Study of the Efficacy and Safety of LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab at Inducing Rapid Renal Response in Patients With Lupus Nephritis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nephritis (LN).
Study identification
- NCT ID
- NCT07611214
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Interventions
- LUPKYNIS Drug
- belimumab, obinutuzumab or anifrolumab Biological
- mycophenolic acid analog (MPAA) Drug
- corticosteroid Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 21, 2026
- Primary completion
- Mar 1, 2029
- Completion
- Mar 1, 2029
- Last update posted
- Aug 2, 2026
2026 – 2029
United States locations
- U.S. sites
- 27
- U.S. states
- 15
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Purushotham & Akther Kotha MD, Inc. | La Mesa | California | 91942 | Recruiting |
| Valerius Medical Group & Research Center of Greater Long Beach, Inc. | Los Alamitos | California | 90720 | Recruiting |
| Western Nephrology & Metabolic Bone Disease, PC | Arvada | Colorado | 80002 | Recruiting |
| Swati Shah MD Rheumatology, LLC | Jacksonville | Florida | 32257 | Recruiting |
| Vida Clinical Research | Kissimmee | Florida | 34741 | Recruiting |
| Life Clinical Trials | Margate | Florida | 33063 | Recruiting |
| CTR Oakwater | Orlando | Florida | 32806 | Recruiting |
| Parris and Associates Rheumatology | Lawrenceville | Georgia | 30044 | Recruiting |
| Accurate Clinical Research, Inc. | Lake Charles | Louisiana | 70605 | Recruiting |
| Arthritis and Rheumatism Associates | Rockville | Maryland | 20850 | Recruiting |
| Kansas City Physician Partners | Kansas City | Missouri | 64151 | Recruiting |
| University of Nevada Las Vegas | Las Vegas | Nevada | 89102 | Recruiting |
| Sahni Rheumatology & Therapy | West Long Branch | New Jersey | 07764 | Recruiting |
| Buffalo Rheumatology and Medicine, PLLC | Orchard Park | New York | 14217 | Recruiting |
| Arthritis and Osteoporosis Consultants of the Carolinas | Charlotte | North Carolina | 28202 | Recruiting |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | Recruiting |
| Rheumatic Disease Associates, Ltd. | Willow Grove | Pennsylvania | 19090 | Recruiting |
| Dunes Clinical Research | Dakota Dunes | South Dakota | 57049 | Recruiting |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | Recruiting |
| Novel Research LLC | Bellaire | Texas | 77401 | Recruiting |
| Liberty Research Center | Dallas | Texas | 75230 | Recruiting |
| Texas Arthritis Center | El Paso | Texas | 79902 | Recruiting |
| Integrative Rheumatology of South Texas | Harlingen | Texas | 78550 | Recruiting |
| Northwest Houston Arthritis Center | Houston | Texas | 77090 | Recruiting |
| Texas Tech University Health Science Center | Lubbock | Texas | 79430 | Recruiting |
| Texas Rheumatology Research Institute, LLC | Plano | Texas | 75024 | Recruiting |
| Nephrology Leaders and Associates, PLLC | Van Vleck | Texas | 77482 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07611214, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 2, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07611214 live on ClinicalTrials.gov.