PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis
Public ClinicalTrials.gov record NCT07611214. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PRESERVE: A Multi-Center Phase 4 Study of the Efficacy and Safety of LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab at Inducing Rapid Renal Response in Patients With Lupus Nephritis
Study identification
- NCT ID
- NCT07611214
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Aurinia Pharmaceuticals Inc.
- Industry
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Interventions
- LUPKYNIS Drug
- belimumab, obinutuzumab or anifrolumab Biological
- mycophenolic acid analog (MPAA) Drug
- corticosteroid Drug
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 21, 2026
- Primary completion
- Mar 1, 2029
- Completion
- Mar 1, 2029
- Last update posted
- Jun 11, 2026
2026 – 2029
United States locations
- U.S. sites
- 15
- U.S. states
- 7
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Purushotham & Akther Kotha MD, Inc. | La Mesa | California | 91942 | Recruiting |
| Valerius Medical Group & Research Center of Greater Long Beach, Inc. | Los Alamitos | California | 90720 | Recruiting |
| Swati Shah MD Rheumatology, LLC | Jacksonville | Florida | 32257 | Recruiting |
| CTR Oakwater | Orlando | Florida | 32806 | Recruiting |
| Parris and Associates Rheumatology | Lawrenceville | Georgia | 30044 | Recruiting |
| Accurate Clinical Research, Inc. | Lake Charles | Louisiana | 70605 | Recruiting |
| Arthritis and Osteoporosis Consultants of the Carolinas | Charlotte | North Carolina | 28202 | Recruiting |
| Joint and Muscle Research Institute | Charlotte | North Carolina | 28204 | Recruiting |
| West Tennessee Research Institute | Jackson | Tennessee | 38305 | Recruiting |
| Novel Research LLC | Bellaire | Texas | 77401 | Recruiting |
| Liberty Research Center | Dallas | Texas | 75230 | Recruiting |
| Integrative Rheumatology of South Texas | Harlingen | Texas | 78550 | Recruiting |
| Northwest Houston Arthritis Center | Houston | Texas | 77090 | Recruiting |
| Texas Rheumatology Research Institute, LLC | Plano | Texas | 75024 | Recruiting |
| Nephrology Leaders and Associates, PLLC | Van Vleck | Texas | 77482 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07611214, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 11, 2026 · Synced Jun 25, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07611214 live on ClinicalTrials.gov.