A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)
Public ClinicalTrials.gov record NCT07614984. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-7262 as Monotherapy and When Coadministered With Enlicitide Decanoate in Adults With Elevated Lipoprotein(a)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Researchers designed a trial medicine called MK-7262 to lower levels of Lp(a) in the blood. Researchers want to learn about giving MK-7262 with another trial medicine called enlicitide (also known as MK-0616 or enlicitide decanoate). Enlicitide is in a group of medicines that lower the amount of low-density lipoprotein cholesterol (LDL-C). The goals of this trial are to evaluate: * if MK-7262 and enlicitide taken together work better than placebo at lowering Lp(a) and LDL-C levels in the blood * if MK-7262 alone works better than placebo at lowering Lp(a) levels in the blood * the safety and tolerability of taking MK-7262 and enlicitide alone and together
Study identification
- NCT ID
- NCT07614984
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 750 participants
Conditions and interventions
Conditions
Interventions
- MK-7262 Drug
- Enlicitide Drug
- Placebo for MK-7262 Drug
- Placebo for enlicitide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 29, 2026
- Primary completion
- Oct 11, 2027
- Completion
- Oct 11, 2027
- Last update posted
- Aug 27, 2026
2026 – 2027
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Cardiovascular - Alexander City ( Site 0158) | Alexander City | Alabama | 35010 | Recruiting |
| AMR Clinical Mobile ( Site 0149) | Mobile | Alabama | 36608 | Recruiting |
| National Heart Institute ( Site 0113) | Beverly Hills | California | 90211-2285 | Recruiting |
| Headlands Research CTR Lincoln ( Site 0127) | Lincoln | California | 95648 | Recruiting |
| Chase Medical Research, LLC ( Site 0163) | Waterbury | Connecticut | 06708 | Recruiting |
| Soffer Health Institute ( Site 0123) | Hollywood | Florida | 33020 | Recruiting |
| Westside Center for Clinical Research ( Site 0161) | Jacksonville | Florida | 32205 | Recruiting |
| Inpatient Research Clinic ( Site 0110) | Miami Lakes | Florida | 33014 | Recruiting |
| Clinical Research Trials of Florida ( Site 0101) | Tampa | Florida | 33607 | Recruiting |
| Conquest Research LLC ( Site 0140) | Winter Park | Florida | 32789 | Recruiting |
| Flourish Research - Bowie ( Site 0106) | Bowie | Maryland | 20715 | Recruiting |
| Velocity Clinical Research Rockville ( Site 0146) | Rockville | Maryland | 20854 | Recruiting |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division ( Site 0132) | Troy | Michigan | 48098 | Recruiting |
| Minneapolis Heart Institute - Minneapolis ( Site 0130) | Minneapolis | Minnesota | 55407 | Recruiting |
| Montana Medical Research, Inc. ( Site 0156) | Missoula | Montana | 59808 | Recruiting |
| New Mexico Clinical Research & Osteoporosis Center ( Site 0119) | Albuquerque | New Mexico | 87106 | Recruiting |
| Laurelton Heart Specialist PC ( Site 0155) | Rosedale | New York | 11422 | Recruiting |
| Velocity Clinical Research, Durham ( Site 0145) | Durham | North Carolina | 27701 | Recruiting |
| Remington-Davis, Inc. ( Site 0107) | Columbus | Ohio | 43215 | Recruiting |
| Holston Medical Group ( Site 0117) | Kingsport | Tennessee | 37660 | Recruiting |
| Center for Cardiometabolic Disease Prevention/Baylor College of Medicine ( Site 0154) | Houston | Texas | 77030 | Recruiting |
| DM Clinical Research ( Site 0115) | Tomball | Texas | 77375 | Recruiting |
| Carient Heart & Vascular - Manassas ( Site 0165) | Manassas | Virginia | 20109 | Recruiting |
| Rainier Clinical Research Center ( Site 0116) | Renton | Washington | 98057 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07614984, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 27, 2026 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07614984 live on ClinicalTrials.gov.