A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia
Public ClinicalTrials.gov record NCT07619118. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomised, Double-Blind, Parallel-Group Study to Assess the Effect of Fixed Dose Combination Laroprovstat/Rosuvastatin Compared With Rosuvastatin on Low-Density Lipoprotein Cholesterol in Patients With Hypercholesterolaemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the effect on low-density lipoprotein-cholesterol (LDL-C) and the safety and tolerability of a fixed dose combination (FDC) of laroprovstat/rosuvastatin versus rosuvastatin alone in patients with hypercholesterolaemia with either a history of a clinical atherosclerotic cardiovascular disease (ASCVD) event or at increased risk for a first clinical ASCVD event.
Study identification
- NCT ID
- NCT07619118
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- laroprovstat/rosuvastatin 1 Combination Product
- laroprovstat/rosuvastatin 2 Combination Product
- laroprovstat/rosuvastatin 3 Combination Product
- laroprovstat/rosuvastatin 4 Combination Product
- Placebo to match laroprovstat/rosuvastatin 1,2,3 Drug
- Placebo to match laroprovstat/rosuvastatin 4 Drug
- Rosuvastatin 1 Drug
- Rosuvastatin 2 Drug
- Rosuvastatin 3 Drug
- Rosuvastatin 4 Drug
- Placebo to match Rosuvastatin Drug
Combination Product · Drug
Eligibility (public fields only)
- Age range
- 18 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 10, 2026 (Actual)
- Primary completion
- May 28, 2027 (Estimated)
- Completion
- May 28, 2027 (Estimated)
- Last update posted
- Oct 5, 2026
2026 – 2027
United States locations
- U.S. sites
- 26
- U.S. states
- 12
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Sun City West | Arizona | 85375 | Recruiting |
| Research Site | Gardena | California | 90247 | Not yet recruiting |
| Research Site | Lomita | California | 90717 | Not yet recruiting |
| Research Site | Pomona | California | 91768 | Recruiting |
| Research Site | Sacramento | California | 95821 | Not yet recruiting |
| Research Site | Jacksonville | Florida | 32216 | Not yet recruiting |
| Research Site | Miami Lakes | Florida | 33016 | Recruiting |
| Research Site | Orlando | Florida | 32807 | Not yet recruiting |
| Research Site | Pembroke Pines | Florida | 33029 | Not yet recruiting |
| Research Site | Conyers | Georgia | 30094 | Recruiting |
| Research Site | Decatur | Georgia | 30030 | Recruiting |
| Research Site | Peachtree Corners | Georgia | 30092 | Not yet recruiting |
| Research Site | Evansville | Indiana | 47714 | Not yet recruiting |
| Research Site | Indianapolis | Indiana | 46260 | Withdrawn |
| Research Site | Zachary | Louisiana | 70791 | Not yet recruiting |
| Research Site | Beltsville | Maryland | 20705 | Recruiting |
| Research Site | Rocky Mount | North Carolina | 27804 | Not yet recruiting |
| Research Site | Statesville | North Carolina | 28625 | Not yet recruiting |
| Research Site | Wilmington | North Carolina | 28401 | Not yet recruiting |
| Research Site | Fargo | North Dakota | 58104 | Not yet recruiting |
| Research Site | Anderson | South Carolina | 29621 | Not yet recruiting |
| Research Site | Bristol | Tennessee | 37620 | Not yet recruiting |
| Research Site | Houston | Texas | 77002 | Not yet recruiting |
| Research Site | Houston | Texas | 77040 | Recruiting |
| Research Site | Mesquite | Texas | 75149 | Recruiting |
| Research Site | Sugar Land | Texas | 77478 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 19 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07619118, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 5, 2026 · Synced Oct 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07619118 live on ClinicalTrials.gov.