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Recruiting Not applicable Interventional

Miro3D Wound Matrix for Treatment of Diabetic Foot Ulcers

ClinicalTrials.gov ID: NCT07632001

Public ClinicalTrials.gov record NCT07632001. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Controlled Multicenter Trial, Examining the Effect of Miro3D Wound Matrix on the Rate of Complete Wound Closure of Chronic Diabetic Foot Ulcers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is designed to evaluate whether the Miro3D Wound Matrix, when used in addition to standard of care, improves healing outcomes in patients with chronic diabetic foot ulcers. Diabetic foot ulcers are a common and serious complication of diabetes and may be difficult to heal despite appropriate treatment. Standard of care typically includes regular wound cleaning, debridement (removal of dead tissue), offloading (reducing pressure on the wound), and moisture-balancing dressings. However, some wounds fail to heal with standard treatment alone. Miro3D Wound Matrix is a three-dimensional, acellular scaffold derived from porcine tissue that is intended to support wound healing. This study will compare outcomes in patients treated with Miro3D plus standard of care versus standard of care alone. Approximately 180 adult subjects with non-healing diabetic foot ulcers will be enrolled at multiple clinical sites in the United States. After a two-week screening period, eligible participants will be randomly assigned to receive either Miro3D in addition to standard of care or standard of care alone. Subjects will be followed for up to 12 weeks with weekly clinic visits. The primary objective of the study is to determine whether treatment with Miro3D increases the rate of complete wound closure and improves reduction in wound size compared to standard of care alone. Safety will also be evaluated by monitoring adverse events throughout the study.

Study identification

NCT ID
NCT07632001
Recruitment status
Recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
Reprise Biomedical, Inc.
Industry
Enrollment
180 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 14, 2026
Primary completion
Feb 28, 2027
Completion
Apr 30, 2027
Last update posted
Aug 12, 2026

2026 – 2027

United States locations

U.S. sites
14
U.S. states
8
U.S. cities
12
Facility City State ZIP Site status
Advanced Foot Care Phoenix Arizona 85032 Recruiting
West Boca Center for Wound Healing Coconut Creek Florida 33073 Not yet recruiting
Solutions Medical Research Coral Gables Florida 33134 Recruiting
Doctors Research Network Miami Florida 33156 Not yet recruiting
Barry University Tamarac Florida 33321 Recruiting
Clinical Trials of New England Hyde Park Massachusetts 02136 Not yet recruiting
Mercy Hyperbaric and Wound Care St Louis Missouri 63128 Not yet recruiting
St. Louis Foot & Ankle St Louis Missouri 63128 Not yet recruiting
Christian Hospital Wound Center St Louis Missouri 63136 Not yet recruiting
Icahn School of Medicine at Mount Sinai New York New York 10029 Not yet recruiting
ABC Podiatry Columbus Ohio 43213 Recruiting
Dynamic Wound Care Oklahoma City Oklahoma 73159 Not yet recruiting
Caring Foot and Ankle Specialists Houston Texas 77035 Recruiting
Vital Heart and Vein Humble Texas 77338 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07632001, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 12, 2026 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07632001 live on ClinicalTrials.gov.

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