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Enrolling by invitation Phase 4 Interventional

CleaRRAflow: Isotonic Solution vs. TPA for IVH Clearance

ClinicalTrials.gov ID: NCT07643493

Public ClinicalTrials.gov record NCT07643493. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 9, 2026, 5:58 AM EST

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Official title

Utility of Continuous Intrathecal TPA Infusion for IVH Clearance With Ventricular Irrigation

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study aims to investigate the effect of continuous tPA irrigation into the ventricles. Investigators believe it may be superior to the traditional every 8-hour bolus dosing and continuous isotonic solution irrigation alone. The protocol plans to analyze blood clearance and functional outcomes in the patients.

Study identification

NCT ID
NCT07643493
Recruitment status
Enrolling by invitation
Study type
Interventional
Phase
Phase 4
Lead sponsor
David Dornbos
Other
Enrollment
80 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2026 (Actual)
Primary completion
May 31, 2028 (Estimated)
Completion
May 31, 2029 (Estimated)
Last update posted
Aug 6, 2026

2026 – 2029

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
UKHC Lexington Kentucky 40536-0298 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07643493, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 6, 2026 · Synced Nov 9, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07643493 live on ClinicalTrials.gov.

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