A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

ClinicalTrials.gov ID: NCT07644559

Public ClinicalTrials.gov record NCT07644559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jun 25, 2026, 7:57 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label Study of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and With Cetuximab, in Patients With Metastatic KRAS G12D-Mutated Pancreatic Cancer (TARGET-D 201)

Study identification

NCT ID: NCT07644559
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Verastem, Inc.; Industry
Enrollment: 180 participants

Conditions and interventions

Conditions

Interventions

VS-7375 Drug
cetuximab Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 15, 2026
Primary completion: May 31, 2027
Completion: Nov 30, 2028
Last update posted: Jun 22, 2026

2026 – 2028

United States locations

U.S. sites: 9
U.S. states: 8
U.S. cities: 9

Facility	City	State	ZIP	Site status
START- Los Angeles	Los Angeles	California	90025	Recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Recruiting
Johns Hopkins University	Baltimore	Maryland	21287	Recruiting
START Midwest	Grand Rapids	Michigan	49546	Recruiting
Washington University	St Louis	Missouri	63110	Recruiting
START New Jersey	East Brunswick	New Jersey	08816	Recruiting
START Dallas	Fort Worth	Texas	76104	Recruiting
START- San Antonio	San Antonio	Texas	78229	Recruiting
START- Mountain Region	West Valley City	Utah	84119	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07644559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jun 22, 2026 · Synced Jun 25, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07644559 live on ClinicalTrials.gov.

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