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Not yet recruiting Not applicable Interventional

WATER IV PCa (AS Sub-study)

ClinicalTrials.gov ID: NCT07650448

Public ClinicalTrials.gov record NCT07650448. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 12:58 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

WATER IV Prostate Cancer: Aquablation Versus Active Surveillance for the Treatment of Localized Prostate Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The WATER IV study is a multicenter, prospective, randomized clinical trial that aims to evaluate the safety and efficacy of Aquablation therapy in men with localized prostate cancer.

Study identification

NCT ID
NCT07650448
Recruitment status
Not yet recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
PROCEPT BioRobotics
Industry
Enrollment
333 participants

Conditions and interventions

Interventions

Device · Other

Eligibility (public fields only)

Age range
45 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 2026 (Estimated)
Primary completion
Dec 2028 (Estimated)
Completion
Dec 2038 (Estimated)
Last update posted
Aug 4, 2026

2026 – 2038

United States locations

U.S. sites
24
U.S. states
16
U.S. cities
24
Facility City State ZIP Site status
Arizona Clinical Trials Chandler Arizona 85224 —
University of Southern California Los Angeles California 90089 —
Tri Valley Urology Murrieta California 92562 —
Boulder Medical Center Boulder Colorado 80304 —
Advanced Research Delray Beach Florida 33484 —
University of Miami Miami Florida 33146 —
Georgia Urology Atlanta Georgia 30328 —
Mountain View Hospital Idaho Falls Idaho 83401 —
University of Chicago Chicago Illinois 60637 —
Endeavor Health Glenview Illinois 60026 —
Johns Hopkins University Baltimore Maryland 21287 —
Kansas City Urology Care North Kansas City Missouri 64116 —
Kearney Urology Center Kearney Nebraska 68847 —
Adult & Pediatric Urology Omaha Nebraska 68114 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
Albany Medical College Albany New York 12208 —
Integrated Medical Professionals, PLLC New York New York 10016 —
University of Rochester Medical Center Rochester New York 14642 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
MUSC Hollings Cancer Center Charleston South Carolina 29425 —
Tidelands Health Urology Murrells Inlet South Carolina 29576 —
Urology Austin Austin Texas 78745 —
Urology Clinics of North Texas Dallas Texas 75231 —
Advocate Aurora Research Institute Sheboygan Wisconsin 53081 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07650448, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 4, 2026 · Synced Oct 23, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07650448 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →