ClinicalTrials.gov record
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
ClinicalTrials.gov ID: NCT07654361
Public ClinicalTrials.gov record NCT07654361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Pivotal Phase 3 Study to Evaluate the Long-Term Efficacy and Safety of Multiple Maintenance Doses of Once Daily Oral Aleniglipron for Chronic Weight Management in Adults With Obesity or Overweight and a Weight-Related Comorbidity
Study identification
- NCT ID
- NCT07654361
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
- Industry
- Enrollment
- 3,600 participants
Conditions and interventions
Conditions
Interventions
- Aleniglipron Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2026
- Primary completion
- Aug 31, 2028
- Completion
- Oct 31, 2028
- Last update posted
- Jun 21, 2026
2026 – 2028
United States locations
- U.S. sites
- 71
- U.S. states
- 32
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| ACCOMPLISH-1 Research Site | Birmingham | Alabama | 35242 | — |
| ACCOMPLISH-1 Research Site | Birmingham | Alabama | 35294-3360 | — |
| ACCOMPLISH-1 Research Site | Phoenix | Arizona | 85225 | — |
| ACCOMPLISH-1 Research Site | Sun City West | Arizona | 85375 | — |
| ACCOMPLISH-1 Research Site | Tucson | Arizona | 85741 | — |
| ACCOMPLISH-1 Research Site | Escondido | California | 92025 | — |
| ACCOMPLISH-1 Research Site | Gardena | California | 92708 | — |
| ACCOMPLISH-1 Research Site | La Jolla | California | 92108 | — |
| ACCOMPLISH-1 Research Site | Modesto | California | 95355 | — |
| ACCOMPLISH-1 Research Site | Rolling Hills Estates | California | 90274 | — |
| ACCOMPLISH-1 Research Site | San Diego | California | 92123 | — |
| ACCOMPLISH-1 Research Site | Clearwater | Florida | 33756 | — |
| ACCOMPLISH-1 Research Site | Leesburg | Florida | 34748 | — |
| ACCOMPLISH-1 Research Site | Miami | Florida | 33136 | — |
| ACCOMPLISH-1 Research Site | Ocala | Florida | 34470 | — |
| ACCOMPLISH-1 Research Site | Ocoee | Florida | 34761 | — |
| ACCOMPLISH-1 Research Site | Pembroke | Florida | 33027 | — |
| ACCOMPLISH-1 Research Site | Tampa | Florida | 33617 | — |
| ACCOMPLISH-1 Research Site | Buford | Georgia | 30046 | — |
| ACCOMPLISH-1 Research Site | Columbus | Georgia | 31904 | — |
| ACCOMPLISH-1 Research Site | Lawrenceville | Georgia | 30046 | — |
| ACCOMPLISH-1 Research Site | Union City | Georgia | 30291 | — |
| ACCOMPLISH-1 Research Site | Woodstock | Georgia | 30189 | — |
| ACCOMPLISH-1 Research Site | Honolulu | Hawaii | 96814-4526 | — |
| ACCOMPLISH-1 Research Site | Meridian | Idaho | 83646 | — |
| ACCOMPLISH-1 Research Site | Rexburg | Idaho | 83440 | — |
| ACCOMPLISH-1 Research Site | Chicago | Illinois | 60637 | — |
| ACCOMPLISH-1 Research Site | Iowa City | Iowa | 52242 | — |
| ACCOMPLISH-1 Research Site | Wichita | Kansas | 67218 | — |
| ACCOMPLISH-1 Research Site | Louisville | Kentucky | 40213 | — |
| ACCOMPLISH-1 Research Site | Baton Rouge | Louisiana | 70808 | — |
| ACCOMPLISH-1 Research Site | Silver Spring | Maryland | 20901-4402 | — |
| ACCOMPLISH-1 Research Site | Methuen | Massachusetts | 01844 | — |
| ACCOMPLISH-1 Research Site | Needham | Massachusetts | 02492 | — |
| ACCOMPLISH-1 Research Site | Ann Arbor | Michigan | 48105-1912 | — |
| ACCOMPLISH-1 Research Site | Mankato | Minnesota | 56001 | — |
| ACCOMPLISH-1 Research Site | Richfield | Minnesota | 55423 | — |
| ACCOMPLISH-1 Research Site | Gulfport | Mississippi | 39503 | — |
| ACCOMPLISH-1 Research Site | Ridgeland | Mississippi | 39157 | — |
| ACCOMPLISH-1 Research Site | Chesterfield | Missouri | 63005 | — |
| ACCOMPLISH-1 Research Site | Hazelwood | Missouri | 63042 | — |
| ACCOMPLISH-1 Research Site | St Louis | Missouri | 63303-3041 | — |
| ACCOMPLISH-1 Research Site | Butte | Montana | 59701 | — |
| ACCOMPLISH-1 Research Site | Missoula | Montana | 59804 | — |
| ACCOMPLISH-1 Research Site | Omaha | Nebraska | 68198-7400 | — |
| ACCOMPLISH-1 Research Site | Las Vegas | Nevada | 89128 | — |
| ACCOMPLISH-1 Research Site | Albany | New York | 12208-3473 | — |
| ACCOMPLISH-1 Research Site | Brooklyn | New York | 11220 | — |
| ACCOMPLISH-1 Research Site | Charlotte | North Carolina | 28210 | — |
| ACCOMPLISH-1 Research Site | Durham | North Carolina | 27710-3000 | — |
| ACCOMPLISH-1 Research Site | Fayetteville | North Carolina | 28304 | — |
| ACCOMPLISH-1 Research Site | New Bern | North Carolina | 28562 | — |
| ACCOMPLISH-1 Research Site | Wilmington | North Carolina | 28401 | — |
| ACCOMPLISH-1 Research Site | Winston-Salem | North Carolina | 27104 | — |
| ACCOMPLISH-1 Research Site | Columbus | Ohio | 43213 | — |
| ACCOMPLISH-1 Research Site | Columbus | Ohio | 43215 | — |
| ACCOMPLISH-1 Research Site | Moore | Oklahoma | 73160 | — |
| ACCOMPLISH-1 Research Site | Portland | Oregon | 97202 | — |
| ACCOMPLISH-1 Research Site | Philadelphia | Pennsylvania | 19152 | — |
| ACCOMPLISH-1 Research Site | Greer | South Carolina | 29651 | — |
| ACCOMPLISH-1 Research Site | Knoxville | Tennessee | 37920 | — |
| ACCOMPLISH-1 Research Site | Austin | Texas | 78704 | — |
| ACCOMPLISH-1 Research Site | Austin | Texas | 78731 | — |
| ACCOMPLISH-1 Research Site | Denison | Texas | 75020-4582 | — |
| ACCOMPLISH-1 Research Site | Houston | Texas | 77040 | — |
| ACCOMPLISH-1 Research Site | Houston | Texas | 77054 | — |
| ACCOMPLISH-1 Research Site | San Antonio | Texas | 78231 | — |
| ACCOMPLISH-1 Research Site | Wylie | Texas | 75098 | — |
| ACCOMPLISH-1 Research Site | Sandy City | Utah | 84094 | — |
| ACCOMPLISH-1 Research Site | St. George | Utah | 84790 | — |
| ACCOMPLISH-1 Research Site | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07654361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 21, 2026 · Synced Jun 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07654361 live on ClinicalTrials.gov.