Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor
Public ClinicalTrials.gov record NCT07673107. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With an Open-Label Period to Evaluate the Efficacy and Safety of AGN-151607-DP (USAN: gemibotulinumtoxinA) for the Treatment of Upper Limb Essential Tremor in Adults
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tasks such as writing, pouring, and eating. This study will assess if AGN-151607-DP is safe and effective by assessing adverse events and change in disease activity in adult participants with UL ET. AGN-151607-DP is an investigational drug being developed to treat UL ET. Participants will be randomly placed in treatment groups to receive either AGN151607-DP or matching placebo. Approximately 94 adult participants with upper limb essential tremor will be enrolled in approximately 40 sites in the United States/Canada. Participants will receive intramuscular injections of AGN-151607-DP or matching placebo. Duration of the study is approximately 72 weeks. The effect of the treatment will be checked by completion of questionnaires and side effects will be monitored by medical assessments.
Study identification
- NCT ID
- NCT07673107
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 94 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 23, 2026 (Actual)
- Primary completion
- Nov 2028 (Estimated)
- Completion
- Nov 2028 (Estimated)
- Last update posted
- Oct 22, 2026
2026 – 2028
United States locations
- U.S. sites
- 18
- U.S. states
- 11
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Neurology Center of Southern California - Carlsbad /ID# 278194 | Carlsbad | California | 92011 | Recruiting |
| Neuro Pain Research Center /ID# 277899 | Fresno | California | 93710 | Recruiting |
| Neurology Center Of North Orange County /ID# 278490 | Fullerton | California | 92835 | Recruiting |
| New England Institute for Clinical Research /ID# 277315 | Stamford | Connecticut | 06905 | Recruiting |
| Parkinson'S Disease & Movement Disorders Center Of Boca Raton /ID# 277079 | Boca Raton | Florida | 33486 | Recruiting |
| Charter Research - Winter Park /ID# 277875 | Orlando | Florida | 32803-1839 | Recruiting |
| Emerald Coast Neurology /ID# 277898 | Pensacola | Florida | 32504-8649 | Recruiting |
| Kansas Institute of Research /ID# 277068 | Overland Park | Kansas | 66211-1358 | Recruiting |
| Dent Neurologic Institute - Amherst /ID# 277242 | Amherst | New York | 14226 | Recruiting |
| True North Neurology /ID# 278118 | Commack | New York | 11725 | Recruiting |
| Neurology - Triad /ID# 277088 | Winston-Salem | North Carolina | 27103 | Recruiting |
| Veracity Neuroscience /ID# 277081 | Memphis | Tennessee | 38157 | Recruiting |
| Texas Neurology /ID# 277067 | Dallas | Texas | 75206-5202 | Recruiting |
| Lone Star Neurology /ID# 278266 | Frisco | Texas | 75035 | Recruiting |
| Houston Methodist Hospital /ID# 277326 | Houston | Texas | 77030 | Recruiting |
| University of Virginia /ID# 278191 | Charlottesville | Virginia | 22908 | Recruiting |
| Inland Northwest Research /ID# 277077 | Spokane | Washington | 99202 | Recruiting |
| Center For Neurological Disorders /ID# 277048 | Greenfield | Wisconsin | 53228 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07673107, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07673107 live on ClinicalTrials.gov.