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Recruiting Phase 3 Interventional

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

ClinicalTrials.gov ID: NCT07684144

Public ClinicalTrials.gov record NCT07684144. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-Blind Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Participants With Obesity or Overweight With Type 2 Diabetes Mellitus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of this trial is to evaluate the long-term efficacy, safety, and tolerability of maridebart cafraglutide in participants with obesity and type 2 diabetes mellitus. Trial 20210182 is extension of trial 20210184 (NCT06858878).

Study identification

NCT ID
NCT07684144
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Amgen
Industry
Enrollment
950 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 29, 2026 (Actual)
Primary completion
Dec 26, 2027 (Estimated)
Completion
Mar 19, 2028 (Estimated)
Last update posted
Oct 5, 2026

2026 – 2028

United States locations

U.S. sites
31
U.S. states
16
U.S. cities
29
Facility City State ZIP Site status
Gilbert Center for Family Medicine Gilbert Arizona 85296 Recruiting
San Fernando Valley Health Institute Canoga Park California 91304 Recruiting
Core Healthcare Group Cerritos California 90703 Recruiting
Velocity Clinical Research Chula Vista La Mesa California 91942 Recruiting
Paradigm Clinical Research Modesto California 95355 Recruiting
Empire Clinical Research Pomona California 91767 Recruiting
San Marcus Research Clinic Inc Miami Florida 33015 Recruiting
Optimus U Corporation Miami Florida 33135 Recruiting
Indago Research and Health Center Miami Lakes Florida 33016 Recruiting
Florida Institute for Clinical Research Orlando Florida 32825 Recruiting
Encore Medical Research of Weston LLC Weston Florida 33331 Recruiting
Conquest Research - Winter Park Winter Park Florida 32789 Recruiting
Endeavor Health Skokie Illinois 60077 Recruiting
Iowa Diabetes Research West Des Moines Iowa 50266 Recruiting
JCCT- Juno Northwest Houston Lenexa Kansas 66219 Recruiting
Alliance for Multispecialty Research Newton Newton Kansas 67114 Recruiting
Alliance for Multispecialty Research LLC Wichita Kansas 67226 Recruiting
Ima Clinical Research- Monroe Monroe Louisiana 71201 Recruiting
Annapolis Internal Medicine, LLC Annapolis Maryland 21401 Recruiting
Alliance for Multispecialty Research - Kansas City Kansas City Missouri 64114 Recruiting
Palm Research Center Inc Las Vegas Nevada 89148 Recruiting
Premier Research Trenton New Jersey 08611 Recruiting
West Clinical Research Morehead City North Carolina 28557 Recruiting
Velocity Clinical Research - Cincinnati Cincinnati Ohio 45242 Recruiting
Velocity Clinical Research - Springdale Cincinnati Ohio 45246 Recruiting
Velocity Clinical Research - Providence East Greenwich Rhode Island 02818 Recruiting
Elligo Clinical Research Center Austin Texas 78704 Recruiting
Johnson County Clinical Trials Juno Bellaire Bellaire Texas 77401 Recruiting
Osvaldo A Brusco MD PA Corpus Christi Texas 78414 Recruiting
Soma Clinical Trials, LLC Denison Texas 75020 Recruiting
Manassas Clinical Research Center Inc Burke Virginia 22015 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07684144, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 5, 2026 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07684144 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →