A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Public ClinicalTrials.gov record NCT07717411. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of trontinemab in participants with biomarker evidence of Alzheimer's Disease (AD) pathology but with no cognitive or functional impairment, who are at risk for progression to mild cognitive impairment (MCI) due to AD or dementia due to AD.
Study identification
- NCT ID
- NCT07717411
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,600 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2026 (Estimated)
- Primary completion
- Sep 3, 2032 (Estimated)
- Completion
- Sep 3, 2032 (Estimated)
- Last update posted
- Oct 13, 2026
2026 – 2032
United States locations
- U.S. sites
- 12
- U.S. states
- 4
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Irvine Center for Clinical Research | Irvine | California | 92614 | Recruiting |
| Healthy Brain Clinic | Long Beach | California | 90804 | Recruiting |
| Oakland Clinical | Oakland | California | 94609 | Recruiting |
| Syrentis Clinical Research | Santa Ana | California | 92705 | Recruiting |
| K2 Medical Research, LLC | Maitland | Florida | 32751 | Recruiting |
| Renstar Medical Research | Ocala | Florida | 34470 | Recruiting |
| Charter Research - Winter Park/Orlando | Orlando | Florida | 32803 | Recruiting |
| Conquest Research - Lake Nona | Orlando | Florida | 32832 | Recruiting |
| Charter Research - Lady Lake/The Villages | The Villages | Florida | 32162 | Recruiting |
| Conquest Research, LLC | Winter Park | Florida | 32789 | Recruiting |
| Basil Clinical | Laurelton | New York | 11413-2016 | Recruiting |
| Sana Research, LLC | Arlington | Virginia | 22205 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07717411, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2026 · Synced Nov 2, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07717411 live on ClinicalTrials.gov.