AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
Public ClinicalTrials.gov record NCT07720271. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Once-daily Oral Zenagamtide in Participants With Obesity (AMAZE 9)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this clinical study is to find out if zenagamtide is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as oral tablets once a day. Participants will either get zenagamtide (the treatment being tested) or Placebo (treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Study identification
- NCT ID
- NCT07720271
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 950 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2026 (Actual)
- Primary completion
- Jun 27, 2028 (Estimated)
- Completion
- Aug 22, 2028 (Estimated)
- Last update posted
- Sep 28, 2026
2026 – 2028
United States locations
- U.S. sites
- 41
- U.S. states
- 18
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group LLC | Anniston | Alabama | 36207 | Recruiting |
| Univ of Alabama Birmingham | Birmingham | Alabama | 35294 | Recruiting |
| Chambliss Clinical Trials LLC | Montgomery | Alabama | 36106 | Recruiting |
| Providence Medical Foundation | Fullerton | California | 92835 | Recruiting |
| Torrance Clinical Research Institute, Inc. | Lomita | California | 90717 | Recruiting |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | Recruiting |
| Univ of Colorado at Denver | Aurora | Colorado | 80045 | Recruiting |
| Brain Matters Research | Delray Beach | Florida | 33445 | Recruiting |
| Northeast Research Institute | Fleming Island | Florida | 32003 | Recruiting |
| Miguel Rebollar PA | Hialeah | Florida | 33012 | Recruiting |
| Jacksonville Ctr Clin Res | Jacksonville | Florida | 32216 | Recruiting |
| South Broward Research LLC | Miramar | Florida | 33027 | Recruiting |
| Clinical Neuroscience Solution | Orlando | Florida | 32801 | Recruiting |
| Florida Institute for Clinical Research, LLC | Orlando | Florida | 32825 | Recruiting |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | Recruiting |
| Hope Clin Res & Wellness | Conyers | Georgia | 30094 | Recruiting |
| East West Medical Research Institute_Honolulu | Honolulu | Hawaii | 96814 | Recruiting |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | Recruiting |
| Clinical Investigation Spec Gurnee | Gurnee | Illinois | 60031 | Recruiting |
| Endeavor Health | Skokie | Illinois | 60077 | Recruiting |
| Evanston Premier Hlthcr Res | Skokie | Illinois | 60077 | Recruiting |
| Midwest Inst For Clin Res | Indianapolis | Indiana | 46260 | Not yet recruiting |
| Northern Pines Hlth Ctr, PC | Buckley | Michigan | 49620 | Recruiting |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | Recruiting |
| Palm Research Center Inc. | Las Vegas | Nevada | 89128 | Recruiting |
| Comprehensive Weight Ctrl Prog | New York | New York | 10021 | Recruiting |
| Medication Mgmnt, LLC_Grnsboro | Greensboro | North Carolina | 27401 | Recruiting |
| Accellacare of Raleigh | Raleigh | North Carolina | 27609 | Recruiting |
| Accellacare-Salisbury PMG Res | Salisbury | North Carolina | 28144 | Recruiting |
| Accellacare and KDCILM, LLC | Wilmington | North Carolina | 28401 | Recruiting |
| Lynn Institute of Norman | Norman | Oklahoma | 73072 | Recruiting |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | Recruiting |
| Medical Uni of SC Charleston | Charleston | South Carolina | 29425 | Recruiting |
| Coastal Carolina Research Ctr | North Charleston | South Carolina | 29405 | Recruiting |
| Hillcrest Clinical Research | Simpsonville | South Carolina | 29681-1538 | Recruiting |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | Recruiting |
| Amarillo Medical Specialists | Amarillo | Texas | 79124 | Recruiting |
| North Texas Endocrine Center | Dallas | Texas | 75231 | Recruiting |
| Washington Cntr Weight Mgmt | Arlington | Virginia | 22206 | Not yet recruiting |
| Health Res of Hampton Roads | Newport News | Virginia | 23606 | Recruiting |
| National Clin Res Inc. | Richmond | Virginia | 23294 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07720271, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 1, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07720271 live on ClinicalTrials.gov.