A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO
Public ClinicalTrials.gov record NCT07734844. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Active-controlled, Multi-center, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tabirafusp Tedromer 5 mg Compared With Intravitreal Aflibercept 2 mg in Participants With Visual Impairment Secondary to Diabetic Macular Edema (DME) - ALTO
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants with Diabetic Macular Edema - ALTO
Study identification
- NCT ID
- NCT07734844
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 910 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2, 2026
- Primary completion
- Aug 30, 2028
- Completion
- Aug 31, 2029
- Last update posted
- Aug 20, 2026
2026 – 2029
United States locations
- U.S. sites
- 9
- U.S. states
- 5
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kodiak Research Center | Glendale | California | 91204 | Recruiting |
| Kodiak Research Center | Pasadena | California | 91107 | Recruiting |
| Kodiak Research Center | St. Petersburg | Florida | 33711 | Recruiting |
| Kodiak Research Center | Hagerstown | Maryland | 21740 | Recruiting |
| Kodiak Research Center | Saint Louis Park | Minnesota | 55416 | Recruiting |
| Kodiak Research Center | Beaufort | South Carolina | 29902 | Recruiting |
| Kodiak Research Center | Charleston | South Carolina | 29414 | Recruiting |
| Kodiak Research Center | Ladson | South Carolina | 29456 | Recruiting |
| Kodiak Research Center | West Columbia | South Carolina | 29169 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07734844, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 20, 2026 · Synced Sep 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07734844 live on ClinicalTrials.gov.