A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Public ClinicalTrials.gov record NCT07742735. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Parallel-group Treatment, Phase 3, Double-blind, Randomized, 2-arm Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 3 placebo-controlled study is planned to further investigate the efficacy, safety, and tolerability of apraglutide in the overall SBS-IF (short bowel syndrome associated with intestinal failure) population during 24 weeks of study treatment. It is expected that approximately 124 participants will be randomized worldwide to either apraglutide or placebo in a 1:1 ratio in this trial.
Study identification
- NCT ID
- NCT07742735
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 124 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2026
- Primary completion
- Sep 30, 2028
- Completion
- Sep 30, 2029
- Last update posted
- Aug 3, 2026
2026 – 2029
United States locations
- U.S. sites
- 17
- U.S. states
- 12
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ronald Reagan UCLA Medical Center, Center for the Health Sciences | Los Angeles | California | 90095 | Not yet recruiting |
| Denver Health Medical Center | Denver | Colorado | 80204 | Not yet recruiting |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | Not yet recruiting |
| University of Florida Health (UF Health) | Gainesville | Florida | 32610 | Not yet recruiting |
| GI Pros | Naples | Florida | 34102 | Recruiting |
| Cleveland Clinic Florida | Weston | Florida | 33331 | Not yet recruiting |
| Loyola University Medical Center | Maywood | Illinois | 60153 | Not yet recruiting |
| UofL Physicians - Colon & Rectal Surgery | Louisville | Kentucky | 40202 | Not yet recruiting |
| Henry Ford Medical Center - Columbus | Novi | Michigan | 48377 | Not yet recruiting |
| Albany Medical Center | Albany | New York | 12208 | Not yet recruiting |
| Mount Sinai Medical Center, RMTI - Intestinal Transplantation & Rehabilitation | New York | New York | 10029 | Not yet recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Not yet recruiting |
| Gastro Health - Clifton | Cincinnati | Ohio | 45219 | Not yet recruiting |
| Cleveland Clinic - Cleveland | Cleveland | Ohio | 44195 | Not yet recruiting |
| OSU Wexner Medical Center | Columbus | Ohio | 43210 | Not yet recruiting |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | Not yet recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 77 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07742735, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07742735 live on ClinicalTrials.gov.