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Recruiting Phase 3 Interventional

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

ClinicalTrials.gov ID: NCT07761117

Public ClinicalTrials.gov record NCT07761117. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 16, 2026, 8:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Cardiovascular Outcomes in Participants With HFpEF and HFmrEF (Elevate-HF)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart failure with preserved ejection fraction (HFpEF)/heart failure with mildly reduced ejection fraction (HFmrEF), irrespective of T2DM status, and who are on background dapagliflozin in addition to other background standard of care.

Study identification

NCT ID
NCT07761117
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
6,950 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 24, 2026 (Actual)
Primary completion
Sep 3, 2029 (Estimated)
Completion
Sep 3, 2029 (Estimated)
Last update posted
Sep 28, 2026

2026 – 2029

United States locations

U.S. sites
120
U.S. states
34
U.S. cities
108
Facility City State ZIP Site status
Research Site Fairhope Alabama 36532 Recruiting
Research Site Anchorage Alaska 99508 Not yet recruiting
Research Site Gilbert Arizona 85295 Not yet recruiting
Research Site Sun City Arizona 85351 Not yet recruiting
Research Site Beverly Hills California 90211 Not yet recruiting
Research Site Huntington Beach California 92647 Not yet recruiting
Research Site Huntington Park California 90255 Not yet recruiting
Research Site Loma Linda California 92354 Not yet recruiting
Research Site Lomita California 90717 Recruiting
Research Site Mather California 95655 Not yet recruiting
Research Site Northridge California 91324 Not yet recruiting
Research Site Palo Alto California 94304 Not yet recruiting
Research Site Redding California 96001 Not yet recruiting
Research Site San Diego California 92117 Not yet recruiting
Research Site Tarzana California 91356 Withdrawn
Research Site Colorado Springs Colorado 80909 Not yet recruiting
Research Site New Haven Connecticut 06519 Not yet recruiting
Research Site Bradenton Florida 34209 Withdrawn
Research Site Hallandale Florida 33009 Not yet recruiting
Research Site Jacksonville Florida 32209 Not yet recruiting
Research Site Lakeland Florida 33813 Not yet recruiting
Research Site Miami Florida 33125 Not yet recruiting
Research Site Miami Florida 33144 Not yet recruiting
Research Site Miami Florida 33176 Not yet recruiting
Research Site Miami Lakes Florida 33014 Withdrawn
Research Site Miami Lakes Florida 33016 Recruiting
Research Site Ocala Florida 34470 Not yet recruiting
Research Site Ocoee Florida 34761 Withdrawn
Research Site Palmetto Bay Florida 33157 Not yet recruiting
Research Site Riverview Florida 33578 Not yet recruiting
Research Site Tampa Florida 33617 Not yet recruiting
Research Site Atlanta Georgia 30303 Not yet recruiting
Research Site Columbus Georgia 31904 Not yet recruiting
Research Site Tucker Georgia 30084 Not yet recruiting
Research Site Champaign Illinois 61822 Withdrawn
Research Site Chicago Illinois 60640 Not yet recruiting
Research Site Gurnee Illinois 60031 Not yet recruiting
Research Site Melrose Park Illinois 60160 Not yet recruiting
Research Site Moline Illinois 61265 Not yet recruiting
Research Site Niles Illinois 60714 Not yet recruiting
Research Site Rockford Illinois 61107 Not yet recruiting
Research Site Schaumburg Illinois 60173 Not yet recruiting
Research Site Winfield Illinois 60190 Not yet recruiting
Research Site Indianapolis Indiana 46254 Not yet recruiting
Research Site Waterloo Iowa 50701 Not yet recruiting
Research Site Leavenworth Kansas 66048 Not yet recruiting
Research Site Wichita Kansas 67214 Not yet recruiting
Research Site Owensboro Kentucky 42301 Not yet recruiting
Research Site Bossier City Louisiana 71111 Not yet recruiting
Research Site Covington Louisiana 70433 Not yet recruiting
Research Site Lafayette Louisiana 70503 Not yet recruiting
Research Site New Orleans Louisiana 70121 Not yet recruiting
Research Site Shreveport Louisiana 71105 Not yet recruiting
Research Site Zachary Louisiana 70791 Not yet recruiting
Research Site Annapolis Maryland 21401 Not yet recruiting
Research Site Baltimore Maryland 21229 Not yet recruiting
Research Site Lanham Maryland 20706 Not yet recruiting
Research Site Oxon Hill Maryland 20745 Not yet recruiting
Research Site Boston Massachusetts 02114 Not yet recruiting
Research Site Boston Massachusetts 02118 Not yet recruiting
Research Site New Bedford Massachusetts 02740 Not yet recruiting
Research Site Worcester Massachusetts 01655 Withdrawn
Research Site Flint Michigan 48503 Recruiting
Research Site Southfield Michigan 48075 Not yet recruiting
Research Site Southfield Michigan 48076 Not yet recruiting
Research Site Troy Michigan 48098 Not yet recruiting
Research Site Bridgeton Missouri 63044 Not yet recruiting
Research Site Kansas City Missouri 64111 Withdrawn
Research Site Kansas City Missouri 64112 Not yet recruiting
Research Site Lincoln Nebraska 68510 Not yet recruiting
Research Site Bridgewater New Jersey 08807 Not yet recruiting
Research Site Millville New Jersey 08332 Not yet recruiting
Research Site Sewell New Jersey 08080 Not yet recruiting
Research Site Trenton New Jersey 08690 Not yet recruiting
Research Site Vineland New Jersey 08360 Not yet recruiting
Research Site Brooklyn New York 11220 Recruiting
Research Site Buffalo New York 14215 Not yet recruiting
Research Site New York New York 10001 Not yet recruiting
Research Site New York New York 10019 Not yet recruiting
Research Site Rosedale New York 11422 Not yet recruiting
Research Site The Bronx New York 10451 Not yet recruiting
Research Site The Bronx New York 10455 Recruiting
Research Site Chapel Hill North Carolina 27514 Not yet recruiting
Research Site Durham North Carolina 27710 Not yet recruiting
Research Site Greensboro North Carolina 27401 Not yet recruiting
Research Site Statesville North Carolina 28677 Not yet recruiting
Research Site Wilmington North Carolina 28401 Not yet recruiting
Research Site Fargo North Dakota 58104 Not yet recruiting
Research Site Grand Forks North Dakota 58201 Not yet recruiting
Research Site Columbus Ohio 43215 Not yet recruiting
Research Site Columbus Ohio 43228 Withdrawn
Research Site Dayton Ohio 45435 Not yet recruiting
Research Site Maumee Ohio 43537 Not yet recruiting
Research Site Oklahoma City Oklahoma 73134 Not yet recruiting
Research Site Bethlehem Pennsylvania 18015 Withdrawn
Research Site Media Pennsylvania 19063 Not yet recruiting
Research Site Philadelphia Pennsylvania 19104 Not yet recruiting
Research Site Philadelphia Pennsylvania 19107 Not yet recruiting
Research Site Smithfield Pennsylvania 15478 Not yet recruiting
Research Site Yardley Pennsylvania 19067 Not yet recruiting
Research Site East Providence Rhode Island 02914 Not yet recruiting
Research Site Spartanburg South Carolina 29303 Not yet recruiting
Research Site Rapid City South Dakota 57701 Not yet recruiting
Research Site Dallas Texas 75216 Not yet recruiting
Research Site DeSoto Texas 75115 Not yet recruiting
Research Site El Paso Texas 79905 Not yet recruiting
Research Site Houston Texas 77025 Not yet recruiting
Research Site Houston Texas 77082 Not yet recruiting
Research Site Humble Texas 77338 Recruiting
Research Site Plano Texas 75093 Withdrawn
Research Site San Antonio Texas 78231 Not yet recruiting
Research Site San Antonio Texas 78257 Not yet recruiting
Research Site Tomball Texas 77375 Recruiting
Research Site Tyler Texas 75701 Not yet recruiting
Research Site Victoria Texas 77901 Not yet recruiting
Research Site Burlington Vermont 05401 Withdrawn
Research Site Arlington Virginia 22205 Not yet recruiting
Research Site Redmond Washington 98052 Recruiting
Research Site Kingwood West Virginia 26537 Not yet recruiting
Research Site Morgantown West Virginia 26505 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 555 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07761117, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2026 · Synced Oct 16, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07761117 live on ClinicalTrials.gov.

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