A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Public ClinicalTrials.gov record NCT07761117. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled, Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Cardiovascular Outcomes in Participants With HFpEF and HFmrEF (Elevate-HF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled, multicenter study to investigate CV outcomes with elecoglipron compared with placebo, in adults with heart failure with preserved ejection fraction (HFpEF)/heart failure with mildly reduced ejection fraction (HFmrEF), irrespective of T2DM status, and who are on background dapagliflozin in addition to other background standard of care.
Study identification
- NCT ID
- NCT07761117
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 6,950 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 27, 2026
- Primary completion
- Sep 2, 2029
- Completion
- Sep 2, 2029
- Last update posted
- Aug 11, 2026
2026 – 2029
United States locations
- U.S. sites
- 69
- U.S. states
- 24
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Fairhope | Alabama | 36532 | — |
| Research Site | Beverly Hills | California | 90211 | — |
| Research Site | Huntington Beach | California | 92647 | — |
| Research Site | Huntington Park | California | 90255 | — |
| Research Site | Loma Linda | California | 92350 | — |
| Research Site | Lomita | California | 90717 | — |
| Research Site | Northridge | California | 91324 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | New Haven | Connecticut | 06519 | — |
| Research Site | Hialeah | Florida | 33012 | — |
| Research Site | Jacksonville | Florida | 32209 | — |
| Research Site | Lakeland | Florida | 33813 | — |
| Research Site | Miami | Florida | 33125 | — |
| Research Site | Miami | Florida | 33144 | — |
| Research Site | Atlanta | Georgia | 30303 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Tucker | Georgia | 30084 | — |
| Research Site | Champaign | Illinois | 61822 | — |
| Research Site | Park Ridge | Illinois | 60068 | — |
| Research Site | Schaumburg | Illinois | 60173 | — |
| Research Site | Indianapolis | Indiana | 46254 | — |
| Research Site | Waterloo | Iowa | 50701 | — |
| Research Site | Bossier City | Louisiana | 71111 | — |
| Research Site | Covington | Louisiana | 70433 | — |
| Research Site | Lafayette | Louisiana | 70503 | — |
| Research Site | New Orleans | Louisiana | 70121 | — |
| Research Site | Shreveport | Louisiana | 71105 | — |
| Research Site | Baltimore | Maryland | 21229 | — |
| Research Site | Lanham | Maryland | 20706 | — |
| Research Site | Oxon Hill | Maryland | 20745 | — |
| Research Site | Boston | Massachusetts | 02114 | — |
| Research Site | Boston | Massachusetts | 02118 | — |
| Research Site | New Bedford | Massachusetts | 02740 | — |
| Research Site | Worcester | Massachusetts | 01655 | — |
| Research Site | Flint | Michigan | 48503 | — |
| Research Site | Southfield | Michigan | 48076 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | St Louis | Missouri | 63136 | — |
| Research Site | Millville | New Jersey | 08332 | — |
| Research Site | Trenton | New Jersey | 08690 | — |
| Research Site | Buffalo | New York | 14215 | — |
| Research Site | New York | New York | 10001 | — |
| Research Site | The Bronx | New York | 10451 | — |
| Research Site | The Bronx | New York | 10455 | — |
| Research Site | Chapel Hill | North Carolina | 27599 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Greensboro | North Carolina | 27410 | — |
| Research Site | Statesville | North Carolina | 28625 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Fargo | North Dakota | 58104 | — |
| Research Site | Grand Forks | North Dakota | 58201 | — |
| Research Site | Columbus | Ohio | 43228 | — |
| Research Site | Dayton | Ohio | 45435 | — |
| Research Site | Maumee | Ohio | 43537 | — |
| Research Site | Oklahoma City | Oklahoma | 73134 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Yardley | Pennsylvania | 19067 | — |
| Research Site | DeSoto | Texas | 75115 | — |
| Research Site | El Paso | Texas | 79905 | — |
| Research Site | Houston | Texas | 77025 | — |
| Research Site | Humble | Texas | 77338 | — |
| Research Site | Lancaster | Texas | 75216 | — |
| Research Site | Plano | Texas | 75093 | — |
| Research Site | San Antonio | Texas | 78231 | — |
| Research Site | Victoria | Texas | 77901 | — |
| Research Site | Burlington | Vermont | 05401 | — |
| Research Site | Arlington | Virginia | 22205 | — |
| Research Site | Redmond | Washington | 98052 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 297 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07761117, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 11, 2026 · Synced Aug 13, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07761117 live on ClinicalTrials.gov.