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Recruiting Phase 3 Interventional

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

ClinicalTrials.gov ID: NCT07770841

Public ClinicalTrials.gov record NCT07770841. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Efficacy and Safety of Once Daily Oral Semaglutide in Adults With Overweight or Obesity

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to see how oral semaglutide, when taken in lower doses help lowering of body weight in participants with excess body weight when compared to 'dummy' tablets (placebo). Results from this study will help select the most optimal lower dose of oral semaglutide that can be used for treating participants living with overweight or obesity.

Study identification

NCT ID
NCT07770841
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
450 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 12, 2026 (Actual)
Primary completion
Feb 22, 2028 (Estimated)
Completion
Apr 11, 2028 (Estimated)
Last update posted
Sep 9, 2026

2026 – 2028

United States locations

U.S. sites
16
U.S. states
12
U.S. cities
16
Facility City State ZIP Site status
Uni of Alabama at Birmingham Birmingham Alabama 35296 Recruiting
Headlands Research California, LLC Escondido California 92025 Recruiting
National Research Institute - Huntington Park Huntington Park California 90255 Recruiting
Los Angeles Institute for Metabolic Research Los Angeles California 90015 Recruiting
ERG Holding Company, LLC / Evolution Research Group, LLC Delray Beach Florida 33445 Recruiting
ERG Holding Company, LLC / Evolution Research Group, LLC Fort Myers Florida 33192 Recruiting
Jedidiah Clinical Research Tampa Florida 33619 Recruiting
East West Med Res Inst Honolulu Hawaii 96814 Recruiting
L-MARC Research Center Louisville Kentucky 40213 Recruiting
StudyMetrix Research LLC City of Saint Peters Missouri 63303 Recruiting
Jubilee Clinical Research, Inc. Las Vegas Nevada 89106 Recruiting
Corvallis Clinic PC Clinical Research Department Corvallis Oregon 97330-3737 Recruiting
UPA Ctr Weight and Eating Dis Philadelphia Pennsylvania 19104 Not yet recruiting
Spartanburg Medical Research Spartanburg South Carolina 29303 Recruiting
Cedar Health Research Dallas Texas 75251 Recruiting
Selma Medical Associates Winchester Virginia 22601-3834 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07770841, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 9, 2026 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07770841 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →