A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
Public ClinicalTrials.gov record NCT07783802. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Clazakizumab in Reducing hsCRP in Adults With Elevated hsCRP and Established ASCVD or at Increased Risk for ASCVD Events
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to measure the change in high-sensitivity C-reactive protein (hsCRP), a marker of inflammation in the body, with clazakizumab compared with placebo in adults who have elevated hsCRP and at increased risk for cardiovascular event. Participation in the study will last about 9 months.
Study identification
- NCT ID
- NCT07783802
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 27, 2026 (Actual)
- Primary completion
- May 2027 (Estimated)
- Completion
- Oct 2027 (Estimated)
- Last update posted
- Oct 8, 2026
2026 – 2027
United States locations
- U.S. sites
- 30
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research, LLC | Huntsville | Alabama | 35801 | Recruiting |
| Pima Heart | Tucson | Arizona | 85741 | Recruiting |
| Eclipse Clinical Research | Tucson | Arizona | 85745 | Recruiting |
| Thrive Clinical Research Group | Glendora | California | 91740 | Recruiting |
| Omega Research Orlando | Altamonte Springs | Florida | 32714 | Recruiting |
| American Research Institute | Cutler Bay | Florida | 33157 | Recruiting |
| K2 Medical Research - Maitland | Maitland | Florida | 32751 | Recruiting |
| Florida Institute For Clinical Research, LLC | Orlando | Florida | 32825 | Recruiting |
| North Georgia Clinical Research | Woodstock | Georgia | 30189 | Recruiting |
| Accellacare - DuPage | Lombard | Illinois | 60148 | Not yet recruiting |
| Franciscan Physician Network - Indiana Heart Physicians | Indianapolis | Indiana | 46237 | Recruiting |
| K2 Medical Research - Foxborough | Foxborough | Massachusetts | 02035 | Recruiting |
| Revival Research Institute, LLC | Dearborn | Michigan | 48126 | Recruiting |
| Olive Branch Family Medical Center | Olive Branch | Mississippi | 38654-3514 | Recruiting |
| Excel Clinical Research, LLC | Las Vegas | Nevada | 89109 | Recruiting |
| Palm Research Center Tenaya | Las Vegas | Nevada | 89128 | Recruiting |
| Rochester Clinical Research - Buffalo | Buffalo | New York | 14217 | Recruiting |
| CHEAR Center LLC | The Bronx | New York | 10455 | Recruiting |
| Velocity Clinical Research, Cincinnati, Springdale | Cincinnati | Ohio | 45246 | Recruiting |
| Suburban Research Associates | West Chester | Pennsylvania | 19380 | Recruiting |
| Cardiology Consultants of Philadelphia Yardley | Yardley | Pennsylvania | 19067 | Recruiting |
| Monroe Biomedical Research - Charleston | North Charleston | South Carolina | 29406 | Recruiting |
| Horizon Clinical Research Group | Cypress | Texas | 77429 | Recruiting |
| Cardiovascular Specialists of Willowbrook | Houston | Texas | 77070 | Recruiting |
| Texas Cardiology Associates of Houston | Kingwood | Texas | 77339 | Recruiting |
| Revival Research Institute, LLC | McKinney | Texas | 75071 | Recruiting |
| Texas Institute of Cardiology, PA | McKinney | Texas | 75071 | Recruiting |
| Ogden Clinic - Canyon View | Ogden | Utah | 84404 | Recruiting |
| Carient Heart & Vascular - Manassas | Manassas | Virginia | 20109 | Recruiting |
| Carient Heart and Vascular LLC-Reston | Reston | Virginia | 20190 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07783802, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07783802 live on ClinicalTrials.gov.