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Recruiting Phase 3 Interventional

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

ClinicalTrials.gov ID: NCT07784270

Public ClinicalTrials.gov record NCT07784270. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 17, 2026, 2:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III Randomized, Double-Blind, Placebo-Controlled Multicentre Trial to Evaluate the Efficacy and Safety of AZD6234 in Participants With Type 2 Diabetes Mellitus and Obesity or Overweight (SELENE 2)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study will evaluate how well AZD6234 works and how safe it is in adults with excess weight or obesity. Efficacy of AZD6234 will be compared to placebo in percent body weight change from baseline at 68 weeks of treatment

Study identification

NCT ID
NCT07784270
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
1,500 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 20, 2026 (Actual)
Primary completion
Aug 8, 2028 (Estimated)
Completion
Aug 8, 2028 (Estimated)
Last update posted
Sep 22, 2026

2026 – 2028

United States locations

U.S. sites
54
U.S. states
22
U.S. cities
50
Facility City State ZIP Site status
Research Site Fairhope Alabama 36532 Recruiting
Research Site Huntsville Alabama 35801 Not yet recruiting
Research Site Mobile Alabama 36608 Not yet recruiting
Research Site Mesa Arizona 85213 Not yet recruiting
Research Site Phoenix Arizona 85044 Not yet recruiting
Research Site Tucson Arizona 85715 Not yet recruiting
Research Site Little Rock Arkansas 72205 Not yet recruiting
Research Site Bakersfield California 93309 Not yet recruiting
Research Site Gardena California 90247 Not yet recruiting
Research Site Lincoln California 95648 Recruiting
Research Site Torrance California 90503 Not yet recruiting
Research Site Walnut Creek California 94598 Not yet recruiting
Research Site Coral Gables Florida 33134 Not yet recruiting
Research Site Fleming Island Florida 32003 Not yet recruiting
Research Site Fort Lauderdale Florida 33316 Not yet recruiting
Research Site Ocoee Florida 34761 Not yet recruiting
Research Site Woodstock Georgia 30189 Not yet recruiting
Research Site Chicago Illinois 60640 Not yet recruiting
Research Site Melrose Park Illinois 60160 Not yet recruiting
Research Site Lenexa Kansas 66219 Recruiting
Research Site Newton Kansas 67114 Not yet recruiting
Research Site Monroe Louisiana 71201 Not yet recruiting
Research Site Beltsville Maryland 20705 Not yet recruiting
Research Site Lanham Maryland 20706 Not yet recruiting
Research Site Oxon Hill Maryland 20745 Not yet recruiting
Research Site Rockville Maryland 20852 Not yet recruiting
Research Site North Dartmouth Massachusetts 02747 Not yet recruiting
Research Site Farmington Hills Michigan 48336 Not yet recruiting
Research Site Fayette Mississippi 39069 Not yet recruiting
Research Site Kansas City Missouri 64111 Not yet recruiting
Research Site Kansas City Missouri 64114 Not yet recruiting
Research Site St Louis Missouri 63141 Not yet recruiting
Research Site Omaha Nebraska 68114 Not yet recruiting
Research Site Omaha Nebraska 68144 Not yet recruiting
Research Site Eatontown New Jersey 07724 Not yet recruiting
Research Site Somerset New Jersey 08873 Not yet recruiting
Research Site Warren Township New Jersey 07059 Not yet recruiting
Research Site Greensboro North Carolina 27408 Withdrawn
Research Site Monroe North Carolina 28112 Not yet recruiting
Research Site Kent Ohio 44240 Not yet recruiting
Research Site Scottdale Pennsylvania 15683 Not yet recruiting
Research Site Franklin Tennessee 37067 Recruiting
Research Site Jackson Tennessee 38305 Not yet recruiting
Research Site Knoxville Tennessee 37938 Not yet recruiting
Research Site DeSoto Texas 75115 Not yet recruiting
Research Site El Paso Texas 79935 Not yet recruiting
Research Site Houston Texas 77099 Not yet recruiting
Research Site Midland Texas 79707 Not yet recruiting
Research Site Pasadena Texas 77504 Not yet recruiting
Research Site San Antonio Texas 78207 Not yet recruiting
Research Site San Antonio Texas 78215 Not yet recruiting
Research Site San Antonio Texas 78251 Not yet recruiting
Research Site Manassas Virginia 20110 Not yet recruiting
Research Site Norfolk Virginia 23504 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 173 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07784270, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 22, 2026 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07784270 live on ClinicalTrials.gov.

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